Kif15-IN-1

Product Name: Kif15-IN-1
CAS No.: 672926-32-8
Chemical Name: Kif15-IN-1
Synonyms: Kif15-IN-1;Kif15 inhibitor 1;Kif-15-IN-1,Kif15IN1,Kif15 IN 1;2-[[(2S)-2-(1,4-Dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester;5-Thiazolecarboxylic acid, 2-[[(2S)-2-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-, ethyl ester
CBNumber: CB22685926
Molecular Formula: C20H22N4O5S
Formula Weight: 430.48
MOL File: 672926-32-8.mol

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Kif15-IN-1 Property

Density: 1.361±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: insoluble in H2O; insoluble in DMSO; ≥19.2 mg/mL in EtOH
form: Solid
pka: 7.73±0.50(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology

Product number: B3280
Product name: Kif15-IN-1
Packaging: 2mg
Price: $341
Updated: 2021/12/16

ChemScene

Product number: CS-2697
Product name: Kif15-IN-1
Purity: 99.53%
Packaging: 5mg
Price: $420
Updated: 2021/12/16

ApexBio Technology

Product number: B3280
Product name: Kif15-IN-1
Packaging: 5mg
Price: $513
Updated: 2021/12/16

ApexBio Technology

Product number: B3280
Product name: Kif15-IN-1
Packaging: 10mg
Price: $733
Updated: 2021/12/16

ChemScene

Product number: CS-2697
Product name: Kif15-IN-1
Purity: 99.53%
Packaging: 50mg
Price: $1800
Updated: 2021/12/16

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Kif15-IN-1 Chemical Properties,Usage,Production

Biological Activity

kif15-in-1, a potent kif15 kinesin inhibitor; inhibits cellular proliferation in various tumor cell lines [1].kif15,also known as kinesin-12 and hklp2, is a motor protein expressed in all cells during mitosis and in postmitotic neurons undergoing axon growth [2]. kif15 is a kinesin-related protein whose mitotic homologues are believed to crosslink and immobilize spindle microtubules.kif15 is involved in maintaining bipolar microtubulespindle apparatusin dividing cells and shares redundant functions with kif11 [3].

References

[1]. preparation of quinazolinediones as kif15 kinesin inhibitors for treating cellular proliferative disorders. pat. appl. publ. (2004), us 20040053948 a1 20040318.
[2]. buster d w, baird d h, yu w, et al. expression of the mitotic kinesin kif15 in postmitotic neurons: implications for neuronal migration and development[j]. journal of neurocytology, 2003, 32(1): 79-96.
[3]. vanneste d, takagi m, imamoto n, et al. the role of hklp2 in the stabilization and maintenance of spindle bipolarity[j]. current biology, 2009, 19(20): 1712-1717.

Kif15-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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Kif15-IN-1 Suppliers

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672926-32-8, Kif15-IN-1Related Search:

Kif15-IN-1

2-[[(2S)-2-(1,4-Dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester

Kif15 inhibitor 1

5-Thiazolecarboxylic acid, 2-[[(2S)-2-(1,4-dihydro-2,4-dioxo-3(2H)-quinazolinyl)-3-methyl-1-oxobutyl]amino]-4-methyl-, ethyl ester

Kif-15-IN-1,Kif15IN1,Kif15 IN 1

672926-32-8