ChemicalBook > CAS DataBase List > VER-49009

VER-49009

Product Name
VER-49009
CAS No.
558640-51-0
Chemical Name
VER-49009
Synonyms
CS-2575;CCT 129397;VER-49009(b;VER-49009;VER 49009;VER49009;5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide;1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-;VER-49009,Inhibitor,CCT-129397,CCT129397,HSP,inhibit,VER 49009,Heat shock proteins,VER49009
CBNumber
CB22705097
Molecular Formula
C19H18ClN3O4
Formula Weight
387.82
MOL File
558640-51-0.mol
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VER-49009 Property

Boiling point:
620.2±55.0 °C(Predicted)
Density 
1.379±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : 100 mg/mL (257.85 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
7.86±0.25(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13131
Product name
VER-49009
Purity
≥98%
Packaging
500μg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
13131
Product name
VER-49009
Purity
≥98%
Packaging
1mg
Price
$190
Updated
2024/03/01
Cayman Chemical
Product number
13131
Product name
VER-49009
Purity
≥98%
Packaging
5mg
Price
$796
Updated
2024/03/01
Cayman Chemical
Product number
13131
Product name
VER-49009
Purity
≥98%
Packaging
10mg
Price
$1394
Updated
2024/03/01
TRC
Product number
V756800
Product name
VER49009
Packaging
10mg
Price
$1485
Updated
2021/12/16
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VER-49009 Chemical Properties,Usage,Production

Uses

VER 49009 is a heat shock protein 90 (HSP90) inhibitor. VER 49009 causes induction of HSP72 and HSP27 alongside depletion of client proteins, including C-RAF, B-RAF, and survivin, and the protein arginine methyltransferase PRMT5.

Definition

ChEBI: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine. It has a role as a Hsp90 inhibitor. It is a member of pyrazoles, a member of resorcinols, a member of monochlorobenzenes, a monomethoxybenzene and an aromatic amide.

VER-49009 Preparation Products And Raw materials

Raw materials

Preparation Products

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558640-51-0, VER-49009Related Search:


  • VER-49009;VER 49009;VER49009
  • CS-2575
  • 5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide
  • CCT 129397
  • 1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-
  • VER-49009,Inhibitor,CCT-129397,CCT129397,HSP,inhibit,VER 49009,Heat shock proteins,VER49009
  • VER-49009(b
  • 558640-51-0