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FluoroMethyl 2-pyridyl sulfone

Product Name
FluoroMethyl 2-pyridyl sulfone
CAS No.
1365765-53-2
Chemical Name
FluoroMethyl 2-pyridyl sulfone
Synonyms
FM-2-pyridyl sulfone;2-Pyridyl fluoromethyl sulfone;FluoroMethyl 2-pyridyl sulfone;2-[(Fluoromethyl)sulfonyl]-pyridine;Pyridine, 2-[(fluoromethyl)sulfonyl]-;Pyridine, 2-[(fluoromethyl)sulfonyl]-2-fluoromethanesulfonylpyridine
CBNumber
CB22709646
Molecular Formula
C6H6FNO2S
Formula Weight
175.18
MOL File
1365765-53-2.mol
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FluoroMethyl 2-pyridyl sulfone Property

Boiling point:
353.2±35.0 °C(Predicted)
Density 
1.348±0.06 g/cm3(Predicted)
pka
-3.04±0.19(Predicted)
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Safety

Safety Statements 
24/25
HS Code 
29309090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Frontier Specialty Chemicals
Product number
JK1711631
Product name
Fluoromethyl2-pyridylsulfone
Purity
98%
Packaging
250mg
Price
$60
Updated
2021/12/16
Apolloscientific
Product number
PC10695
Product name
Fluoromethyl2-pyridylsulfone
Purity
95%
Packaging
250mg
Price
$104
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK1711631
Product name
Fluoromethyl2-pyridylsulfone
Purity
98%
Packaging
1g
Price
$178
Updated
2021/12/16
Apolloscientific
Product number
PC10695
Product name
Fluoromethyl2-pyridylsulfone
Purity
95%
Packaging
1g
Price
$320
Updated
2021/12/16
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FluoroMethyl 2-pyridyl sulfone Chemical Properties,Usage,Production

Description

Fluoromethyl 2-pyridyl sulfone and its derivatives can be used as novel monofluoromethylation reagents. The monofluorinated sulfinate intermediates during the monofluoroolefination of aldehydes and ketones can be halogenated in situ to afford mono- and dihalofluoroalkyl compounds. The coupling reaction between iodofluoromethyl 2-pyridyl sulfone and aryl iodides mediated by copper can be used to prepare monofluoromethyl arenes and heteroarenes.

Chemical Properties

white solid

Reactions

(1) Dihalofluoromethylation of aldehydes and ketones.
(2) Halofluoroalkylation of aldehydes.

(3) Monofluoromethylation of arenes and heteroarenes.

References

[1] YANCHUAN ZHAO Jinbo H Bing Gao. From Olefination to Alkylation: In-Situ Halogenation of Julia–Kocienski Intermediates Leading to Formal Nucleophilic Iodo- and Bromodifluoromethylation of Carbonyl Compounds[J]. Journal of the American Chemical Society, 2012, 134 13: 5790-5793. DOI:10.1021/ja301601b.
[2] YANCHUAN ZHAO. Copper-Mediated Fluoroalkylation of Aryl Iodides Enables Facile Access to Diverse Fluorinated Compounds: The Important Role of the (2-Pyridyl)sulfonyl Group[J]. Organic Letters, 2012, 14 23: 6080-6083. DOI:10.1021/ol3029737.

FluoroMethyl 2-pyridyl sulfone Preparation Products And Raw materials

Raw materials

Preparation Products

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FluoroMethyl 2-pyridyl sulfone Suppliers

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View Lastest Price from FluoroMethyl 2-pyridyl sulfone manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
FluoroMethyl 2-pyridyl sulfone 1365765-53-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09

1365765-53-2, FluoroMethyl 2-pyridyl sulfoneRelated Search:


  • FluoroMethyl 2-pyridyl sulfone
  • 2-[(Fluoromethyl)sulfonyl]-pyridine
  • Pyridine, 2-[(fluoromethyl)sulfonyl]-
  • FM-2-pyridyl sulfone
  • 2-Pyridyl fluoromethyl sulfone
  • Pyridine, 2-[(fluoromethyl)sulfonyl]-2-fluoromethanesulfonylpyridine
  • 1365765-53-2