ChemicalBook > CAS DataBase List > SBC110,736

SBC110,736

Product Name
SBC110,736
CAS No.
1629166-02-4
Chemical Name
SBC110,736
Synonyms
SBC110,736;SBC-1107326;SBC-1107326(b);SBC-110736 ,S0118;SBC110736;SBC 110736;SBC-110736, 10 mM in DMSO;N-(4-(2-Phenyl-4-(p-tolyl)piperazine-1-carbonyl)phenyl)acetamide;N-(4-{[4-(4-Methylphenyl)-2-phenyl-1-piperazinyl]carbonyl}phenyl)acetamid;Acetamide, N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-;cholesterol,inhibit,Ser/Thr Protease,diet,Serine endopeptidases,Inhibitor,Threonine proteases,SBC 110736,SBC-110736,high,fat,Serine proteases
CBNumber
CB22730556
Molecular Formula
C26H27N3O2
Formula Weight
413.51
MOL File
1629166-02-4.mol
More
Less

SBC110,736 Property

Boiling point:
681.1±55.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO:64.0(Max Conc. mg/mL);154.77(Max Conc. mM)
form 
A crystalline solid
pka
14.77±0.70(Predicted)
color 
White to off-white
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
23103
Product name
SBC-110736
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
23103
Product name
SBC-110736
Packaging
5mg
Price
$134
Updated
2024/03/01
Cayman Chemical
Product number
23103
Product name
SBC-110736
Packaging
10mg
Price
$231
Updated
2024/03/01
Cayman Chemical
Product number
23103
Product name
SBC-110736
Packaging
25mg
Price
$485
Updated
2024/03/01
Biosynth Carbosynth
Product number
FS145153
Product name
SBC 110736
Packaging
10mg
Price
$125
Updated
2021/12/16
More
Less

SBC110,736 Chemical Properties,Usage,Production

Uses

SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1[1].

in vivo

SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels[1].

References

[1] Sherin Salaheldin Abdel-Meguid, et al. Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases. WO2014150395A1.

SBC110,736 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

SBC110,736 Suppliers

HangZhou YuHao Chemical Technology Co., Ltd.
Tel
0571-82693216
Fax
0571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
2028
Advantage
58
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Rechem science Co., Ltd.
Tel
021-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2990
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
Advantage
58
Shanghai Yu Ben Biotechnology Co., Ltd.
Tel
021-61350663 15502154572
Fax
-
Email
1639466865@qq.com
Country
China
ProdList
498
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58

1629166-02-4, SBC110,736Related Search:


  • SBC110,736
  • SBC-1107326
  • N-(4-{[4-(4-Methylphenyl)-2-phenyl-1-piperazinyl]carbonyl}phenyl)acetamid
  • SBC110736;SBC 110736
  • Acetamide, N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-
  • SBC-1107326(b)
  • cholesterol,inhibit,Ser/Thr Protease,diet,Serine endopeptidases,Inhibitor,Threonine proteases,SBC 110736,SBC-110736,high,fat,Serine proteases
  • N-(4-(2-Phenyl-4-(p-tolyl)piperazine-1-carbonyl)phenyl)acetamide
  • SBC-110736, 10 mM in DMSO
  • SBC-110736 ,S0118
  • 1629166-02-4