ChemicalBook > CAS DataBase List > SBC110,736
SBC110,736
- Product Name
- SBC110,736
- CAS No.
- 1629166-02-4
- Chemical Name
- SBC110,736
- Synonyms
- SBC110,736;SBC-1107326;SBC-1107326(b);SBC-110736 ,S0118;SBC110736;SBC 110736;SBC-110736, 10 mM in DMSO;N-(4-(2-Phenyl-4-(p-tolyl)piperazine-1-carbonyl)phenyl)acetamide;N-(4-{[4-(4-Methylphenyl)-2-phenyl-1-piperazinyl]carbonyl}phenyl)acetamid;Acetamide, N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-;cholesterol,inhibit,Ser/Thr Protease,diet,Serine endopeptidases,Inhibitor,Threonine proteases,SBC 110736,SBC-110736,high,fat,Serine proteases
- CBNumber
- CB22730556
- Molecular Formula
- C26H27N3O2
- Formula Weight
- 413.51
- MOL File
- 1629166-02-4.mol
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SBC110,736 Property
- Boiling point:
- 681.1±55.0 °C(Predicted)
- Density
- 1.204±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO:64.0(Max Conc. mg/mL);154.77(Max Conc. mM)
- form
- A crystalline solid
- pka
- 14.77±0.70(Predicted)
- color
- White to off-white
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 23103
- Product name
- SBC-110736
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23103
- Product name
- SBC-110736
- Packaging
- 5mg
- Price
- $134
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23103
- Product name
- SBC-110736
- Packaging
- 10mg
- Price
- $231
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 23103
- Product name
- SBC-110736
- Packaging
- 25mg
- Price
- $485
- Updated
- 2024/03/01
Biosynth Carbosynth
- Product number
- FS145153
- Product name
- SBC 110736
- Packaging
- 10mg
- Price
- $125
- Updated
- 2021/12/16
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SBC110,736 Chemical Properties,Usage,Production
Uses
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1[1].
in vivo
SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels[1].
References
[1] Sherin Salaheldin Abdel-Meguid, et al. Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases. WO2014150395A1.
SBC110,736 Preparation Products And Raw materials
Raw materials
Preparation Products
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SBC110,736 Suppliers
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