CZC-54252

ChemicalBook > CAS DataBase List > CZC-54252

Product Name: CZC-54252
CAS No.: 1191911-27-9
Chemical Name: CZC-54252
Synonyms: CS-1730;CZC-54252;CZC-54252, >98%;CZC 54252;CZC54252;CZC 54252 hydrochloride;CZC-54252, 10 mM in DMSO;N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide;LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor;N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide;Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-
CBNumber: CB22738769
Molecular Formula: C22H25ClN6O4S
Formula Weight: 504.99
MOL File: 1191911-27-9.mol

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CZC-54252 Property

Boiling point:: 718.1±70.0 °C(Predicted)
Density: 1.452±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMF: 20 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 10 mg/mL
form: Powder
pka: 8.50±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 17998
Product name: CZC 54252
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 17998
Product name: CZC 54252
Purity: ≥98%
Packaging: 5mg
Price: $130
Updated: 2024/03/01

Cayman Chemical

Product number: 17998
Product name: CZC 54252
Purity: ≥98%
Packaging: 10mg
Price: $235
Updated: 2024/03/01

Cayman Chemical

Product number: 17998
Product name: CZC 54252
Purity: ≥98%
Packaging: 25mg
Price: $533
Updated: 2024/03/01

Tocris

Product number: 4534
Product name: CZC54252hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $906
Updated: 2021/12/16

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CZC-54252 Chemical Properties,Usage,Production

Uses

CZC 54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations are associated with familial Parkinson''s disease and a potential therapeutic target.

Definition

ChEBI: CZC-25146 is a member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is an aminopyrimidine, a member of morpholines, an aromatic ether, an organochlorine compound, a sulfonamide and a secondary amino compound.

CZC-54252 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CZC-54252 manufacturers

Career Henan Chemica Co

Product: CZC-54252 1191911-27-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: MIn98%HPLC/LC
Supply Ability: 100KGS
Release date: 2020-10-29

1191911-27-9, CZC-54252Related Search:

N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide

CZC 54252 hydrochloride

CZC-54252

CS-1730

N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride

CZC 54252;CZC54252

CZC-54252, >98%

Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-

N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide

LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor

CZC-54252, 10 mM in DMSO

1191911-27-9

C22H25ClN6O4S

C22H25ClN6O4SHCl

Inhibitors