ChemicalBook > CAS DataBase List > CZC-54252
CZC-54252
- Product Name
- CZC-54252
- CAS No.
- 1191911-27-9
- Chemical Name
- CZC-54252
- Synonyms
- CS-1730;CZC-54252;CZC-54252, >98%;CZC 54252;CZC54252;CZC 54252 hydrochloride;N-(2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)phenyl)methanesulfonamide;LRRK2,LRRK2-G2019S,inhibit,neuronal,CZC-54252,injury,neuroprotective,Leucine-rich repeat kinase 2,Inhibitor;N-{2-[(5-chloro-2-{[2-methoxy-4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]phenyl}methanesulfonamide;Methanesulfonamide, N-[2-[[5-chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-;N-[2-[[5-Chloro-2-[[2-methoxy-4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]amino]phenyl]methanesulfonamide hydrochloride
- CBNumber
- CB22738769
- Molecular Formula
- C22H25ClN6O4S
- Formula Weight
- 504.99
- MOL File
- 1191911-27-9.mol
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CZC-54252 Property
- Boiling point:
- 718.1±70.0 °C(Predicted)
- Density
- 1.452±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF: 20 mg/mL; DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL; DMSO: 10 mg/mL
- form
- Powder
- pka
- 8.50±0.10(Predicted)
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 17998
- Product name
- CZC 54252
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17998
- Product name
- CZC 54252
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $130
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17998
- Product name
- CZC 54252
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $235
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 17998
- Product name
- CZC 54252
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $533
- Updated
- 2024/03/01
Tocris
- Product number
- 4534
- Product name
- CZC54252hydrochloride
- Purity
- ≥98%(HPLC)
- Packaging
- 50
- Price
- $906
- Updated
- 2021/12/16
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CZC-54252 Chemical Properties,Usage,Production
Uses
CZC 54252 is an inhibitor of leucine-rich repeat kinase 2 (LRRK2). LRRK2 mutations are associated with familial Parkinson''s disease and a potential therapeutic target.
Definition
ChEBI: CZC-25146 is a member of the class of aminopyrimidines that is 2,6-diamino-5-chloropyrimidine in which the amino groups at positions 2 and 6 are respectively carrying 2-methoxy-4-(morpholin-4-yl)phenyl and 2-(methanesulfonylamino)phenyl substituents. It is an inhibitor of the Parkinson's disease kinase LRRK2. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is an aminopyrimidine, a member of morpholines, an aromatic ether, an organochlorine compound, a sulfonamide and a secondary amino compound.
CZC-54252 Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from CZC-54252 manufacturers
Career Henan Chemica Co
- Product
- CZC-54252 1191911-27-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- MIn98%HPLC/LC
- Supply Ability
- 100KGS
- Release date
- 2020-10-29