4-(PYRROLIDIN-1-YL)BENZYLAMINE
- Product Name
- 4-(PYRROLIDIN-1-YL)BENZYLAMINE
- CAS No.
- 114365-04-7
- Chemical Name
- 4-(PYRROLIDIN-1-YL)BENZYLAMINE
- Synonyms
- ST5334145;AKOS B022103;ART-CHEM-BB B022103;(4-(Pyrrolidin-1-yl);4-PYRROLIDINOBENZYLAMINE;4-(PYRROLIDIN-1-YL)BENZYLAMINE;4-(Pyrrolidin-1-yl)benzylamine97%;4-(Pyrrolidin-1-yl)benzylamine 97%;[4-(1-PYRROLIDINYL)PHENYL]METHYLAMINE;[4-(1-PYRROLIDINYL)PHENYL]METHANAMINE
- CBNumber
- CB2274829
- Molecular Formula
- C11H16N2
- Formula Weight
- 176.26
- MOL File
- 114365-04-7.mol
4-(PYRROLIDIN-1-YL)BENZYLAMINE Property
- Melting point:
- 47-50°
- Boiling point:
- 327.0±25.0 °C(Predicted)
- Density
- 1.075±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 9.66±0.10(Predicted)
- Appearance
- Light brown to brown Solid
Safety
- Hazard Codes
- C,Xi
- RIDADR
- UN3259
- Hazard Note
- Corrosive
- HazardClass
- IRRITANT
- HS Code
- 2933998090
N-Bromosuccinimide Price
- Product number
- P840430
- Product name
- (4-(Pyrrolidin-1-yl)phenyl)methanamine
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR6730
- Product name
- 4-(Pyrrolidin-1-yl)benzylamine
- Purity
- 97%
- Packaging
- 250mg
- Price
- $48
- Updated
- 2021/12/16
- Product number
- 3H30-1-30
- Product name
- (4-(Pyrrolidin-1-yl)phenyl)methanamine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $56
- Updated
- 2021/12/16
- Product number
- 037287
- Product name
- 4-Pyrrolidin-1-yl-benzylamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $60
- Updated
- 2021/12/16
- Product number
- OR6730
- Product name
- 4-(Pyrrolidin-1-yl)benzylamine
- Purity
- 97%
- Packaging
- 1g
- Price
- $102
- Updated
- 2021/12/16
4-(PYRROLIDIN-1-YL)BENZYLAMINE Chemical Properties,Usage,Production
Synthesis
10282-30-1
114365-04-7
General procedure for the synthesis of [4-(1-pyrrolidinyl)phenyl]methanamine from 4-(1-pyrrolidinyl)benzonitrile: 1. 4-(1-pyrrolidinyl)benzonitrile (1.68 g, 9.76 mmol) was dissolved in 10 mL of ether at 0 °C and slowly added dropwise to LiAlH4 (2 equiv, 742 mg) suspended in ether. 2. The reaction mixture was stirred at room temperature for 24 hours. 3. Upon completion of the reaction, water was carefully added to quench the reaction, followed by filtration and washing of the solid salt with ether. 4. The organic phase was separated and dried over anhydrous sodium sulfate, then the solvent was evaporated to give 1.48 g of a yellow oily product in 86% yield. 5. The product was subjected to 1HNMR. 5. The product was characterized by 1HNMR (DMSO, 200 MHz): δ 1.60 (2H, bs), 1.93 (4H, m), 3.17 (4H, m), 3.57 (2H, s), 6.46 (2H, d, J = 8.6 Hz), 7.09 (2H, d, J = 8.4 Hz).
References
[1] Journal of Medicinal Chemistry, 2007, vol. 50, # 15, p. 3651 - 3660
[2] Patent: WO2011/120604, 2011, A1. Location in patent: Page/Page column 44; 45; 134
[3] Patent: EP2377850, 2011, A1. Location in patent: Page/Page column 17
4-(PYRROLIDIN-1-YL)BENZYLAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(PYRROLIDIN-1-YL)BENZYLAMINE manufacturers
- Product
- 4-(PYRROLIDIN-1-YL)BENZYLAMINE 114365-04-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 4-(PYRROLIDIN-1-YL)BENZYLAMINE 114365-04-7
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-13