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1-(2-Bromobenzyl)-1H-imidazole

Product Name
1-(2-Bromobenzyl)-1H-imidazole
CAS No.
72459-45-1
Chemical Name
1-(2-Bromobenzyl)-1H-imidazole
Synonyms
1-(2-Bromobenzyl)-1H-imidazole;1-[(2-bromophenyl)methyl]imidazole;1-[(2-bromophenyl)methyl]-1H-imidazole;1H-Imidazole, 1-[(2-bromophenyl)methyl]-
CBNumber
CB22748717
Molecular Formula
C10H9BrN2
Formula Weight
237.1
MOL File
72459-45-1.mol
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1-(2-Bromobenzyl)-1H-imidazole Property

Boiling point:
366.1±17.0 °C(Predicted)
Density 
1.44±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
6.57±0.12(Predicted)
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Safety

HS Code 
2933299090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Apolloscientific
Product number
OR950321
Product name
1-(2-Bromobenzyl)-1H-imidazole
Purity
>98%
Packaging
100mg
Price
$385
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-BG
Product name
1-(2-Bromobenzyl)-1H-imidazole
Purity
98.0%
Packaging
100mg
Price
$424
Updated
2021/12/16
Apolloscientific
Product number
OR950321
Product name
1-(2-Bromobenzyl)-1H-imidazole
Purity
>98%
Packaging
250mg
Price
$704
Updated
2021/12/16
SynQuest Laboratories
Product number
3H32-9-BG
Product name
1-(2-Bromobenzyl)-1H-imidazole
Purity
98.0%
Packaging
250mg
Price
$776
Updated
2021/12/16
AK Scientific
Product number
5263CU
Product name
1-(2-Bromobenzyl)-1H-imidazole
Packaging
5g
Price
$1234
Updated
2021/12/16
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1-(2-Bromobenzyl)-1H-imidazole Chemical Properties,Usage,Production

Synthesis

288-32-4

95-46-5

72459-45-1

1. 2-Bromotoluene (20 g, 117 mmol), N-bromosuccinimide (22.0 g, 123 mmol) and azodiisobutyronitrile (1 g) were dissolved in dry carbon tetrachloride (200 mL) under nitrogen protection and heated to reflux for 16 hours. 2. After completion of the reaction, cooled to room temperature and filtered. 3. To the filtrate, imidazole (15.9 g, 234 mmol) and potassium carbonate (33 g, 234 mmol) were added and refluxed under nitrogen protection for 5 hours. 4. The completion of the reaction was monitored by LC-MS and the reaction mixture was filtered. 5. The filtrate was concentrated and the residue was dissolved in dichloromethane (100 mL) and washed with water (2 x 50 mL). 6. Separate the organic phase, dry with anhydrous sodium sulfate, filter and concentrate. 7. Purify the residue using fast silica gel column chromatography to afford 1-(2-bromobenzyl)-1H-imidazole (20 g).

References

[1] Patent: CN107312005, 2017, A. Location in patent: Paragraph 0103; 0104; 0105; 0106

1-(2-Bromobenzyl)-1H-imidazole Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-Bromobenzyl)-1H-imidazole Suppliers

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72459-45-1, 1-(2-Bromobenzyl)-1H-imidazoleRelated Search:


  • 1-(2-Bromobenzyl)-1H-imidazole
  • 1-[(2-bromophenyl)methyl]imidazole
  • 1-[(2-bromophenyl)methyl]-1H-imidazole
  • 1H-Imidazole, 1-[(2-bromophenyl)methyl]-
  • 72459-45-1