1-(2-Bromobenzyl)-1H-imidazole
- Product Name
- 1-(2-Bromobenzyl)-1H-imidazole
- CAS No.
- 72459-45-1
- Chemical Name
- 1-(2-Bromobenzyl)-1H-imidazole
- Synonyms
- 1-(2-Bromobenzyl)-1H-imidazole;1-[(2-bromophenyl)methyl]imidazole;1-[(2-bromophenyl)methyl]-1H-imidazole;1H-Imidazole, 1-[(2-bromophenyl)methyl]-
- CBNumber
- CB22748717
- Molecular Formula
- C10H9BrN2
- Formula Weight
- 237.1
- MOL File
- 72459-45-1.mol
1-(2-Bromobenzyl)-1H-imidazole Property
- Boiling point:
- 366.1±17.0 °C(Predicted)
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.57±0.12(Predicted)
Safety
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR950321
- Product name
- 1-(2-Bromobenzyl)-1H-imidazole
- Purity
- >98%
- Packaging
- 100mg
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 3H32-9-BG
- Product name
- 1-(2-Bromobenzyl)-1H-imidazole
- Purity
- 98.0%
- Packaging
- 100mg
- Price
- $424
- Updated
- 2021/12/16
- Product number
- OR950321
- Product name
- 1-(2-Bromobenzyl)-1H-imidazole
- Purity
- >98%
- Packaging
- 250mg
- Price
- $704
- Updated
- 2021/12/16
- Product number
- 3H32-9-BG
- Product name
- 1-(2-Bromobenzyl)-1H-imidazole
- Purity
- 98.0%
- Packaging
- 250mg
- Price
- $776
- Updated
- 2021/12/16
- Product number
- 5263CU
- Product name
- 1-(2-Bromobenzyl)-1H-imidazole
- Packaging
- 5g
- Price
- $1234
- Updated
- 2021/12/16
1-(2-Bromobenzyl)-1H-imidazole Chemical Properties,Usage,Production
Synthesis
288-32-4
95-46-5
72459-45-1
1. 2-Bromotoluene (20 g, 117 mmol), N-bromosuccinimide (22.0 g, 123 mmol) and azodiisobutyronitrile (1 g) were dissolved in dry carbon tetrachloride (200 mL) under nitrogen protection and heated to reflux for 16 hours. 2. After completion of the reaction, cooled to room temperature and filtered. 3. To the filtrate, imidazole (15.9 g, 234 mmol) and potassium carbonate (33 g, 234 mmol) were added and refluxed under nitrogen protection for 5 hours. 4. The completion of the reaction was monitored by LC-MS and the reaction mixture was filtered. 5. The filtrate was concentrated and the residue was dissolved in dichloromethane (100 mL) and washed with water (2 x 50 mL). 6. Separate the organic phase, dry with anhydrous sodium sulfate, filter and concentrate. 7. Purify the residue using fast silica gel column chromatography to afford 1-(2-bromobenzyl)-1H-imidazole (20 g).
References
[1] Patent: CN107312005, 2017, A. Location in patent: Paragraph 0103; 0104; 0105; 0106
1-(2-Bromobenzyl)-1H-imidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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