ChemicalBook > CAS DataBase List > (XYL)2P(O)H

(XYL)2P(O)H

Product Name
(XYL)2P(O)H
CAS No.
187344-92-9
Chemical Name
(XYL)2P(O)H
Synonyms
(XYL)2P(O)H;Bis(3,5-diMethylphenyl)phosphi;BIS(3,5-DIMETHYLPHENYL)PHOSPHINE OXIDE;bis(3,5-dimethylphenyl)-oxophosphanium;bis(3,5 -dimethylpheny)phosphine oxide;Bis(3,5-dimethylphenyl)phosphineOxide>Phosphine oxide,bis(3,5-diMethylphenyl)-;Bis(3,5-dimethylphenyl)phosphine oxide ,97%;1-[(3,5-diMethylphenyl)phosphoryl]-3,5-diMethylbenzene
CBNumber
CB2293464
Molecular Formula
C16H19OP
Formula Weight
258.3
MOL File
187344-92-9.mol
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(XYL)2P(O)H Property

Melting point:
82-84℃
Boiling point:
414.8±55.0 °C(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Powder
color 
White
InChI
InChI=1S/C16H19OP/c1-11-5-12(2)8-15(7-11)18(17)16-9-13(3)6-14(4)10-16/h5-10,18H,1-4H3
InChIKey
AWAYSUMOANJULO-UHFFFAOYSA-N
SMILES
P(=O)(C1=CC(C)=CC(C)=C1)C1=CC(C)=CC(C)=C1
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Safety

Risk Statements 
20/21/22
Safety Statements 
26-36/37/39
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B4390
Product name
Bis(3,5-dimethylphenyl)phosphine Oxide
Purity
>97.0%(HPLC)
Packaging
1g
Price
$53
Updated
2025/07/31
TCI Chemical
Product number
B4390
Product name
Bis(3,5-dimethylphenyl)phosphine Oxide
Purity
>97.0%(HPLC)
Packaging
5g
Price
$158
Updated
2025/07/31
Frontier Specialty Chemicals
Product number
JK351296
Product name
Bis(3,5-dimethylphenyl)phosphine Oxide
Purity
97%
Packaging
1g
Price
$36
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB149763
Product name
Bis(3,5-dimethylphenyl)phosphine Oxide
Packaging
1g
Price
$70
Updated
2021/12/16
AK Scientific
Product number
9774AA
Product name
Bis(3,5-dimethylphenyl)phosphine Oxide
Packaging
1g
Price
$76
Updated
2021/12/16
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(XYL)2P(O)H Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

suzuki reaction

Synthesis

556-96-7

187344-92-9

General procedure for the synthesis of bis(3,5-dimethylphenyl)phosphine oxide from 3,5-dimethylbromobenzene: 1-bromo-3,5-dimethylbenzene (129.5 g, 3.5 eq.) was slowly added to a suspension of magnesium shavings (17.0 g, 3.5 eq.) in tetrahydrofuran (THF, 770 mL) while controlling the internal temperature to maintain at 40-50 °C. The reaction mixture was stirred continuously at 40-50 °C for 1 h and subsequently cooled to 0 °C. Triethyl phosphate ((EtO)3PO, 27.7 g, 0.200 mol) was added dropwise over 30 min and stirring was continued for 1 h at 0 °C. Upon completion of the reaction, the reaction was quenched with 6 M aqueous hydrochloric acid (260 mL) and the mixture was extracted with dichloromethane (CH2Cl2, 260 mL x 3) and washed with water (H2O, 130 mL x 2). After concentration under vacuum, the residue was purified by silica gel column chromatography to afford bis(3,5-dimethylphenyl)phosphine oxide (49.7 g, 96% yield) as a light yellow solid.

References

[1] Chemistry Letters, 2013, vol. 42, # 9, p. 1035 - 1037
[2] Chemical Communications, 2013, vol. 49, # 82, p. 9425 - 9427
[3] Patent: WO2014/196930, 2014, A1. Location in patent: Page/Page column 21; 22
[4] Patent: EP1452537, 2004, A1. Location in patent: Page 25
[5] Zeitschrift fur Anorganische und Allgemeine Chemie, 2016, vol. 642, # 6, p. 508 - 514

(XYL)2P(O)H Preparation Products And Raw materials

Raw materials

Ethanol 5-Bromo-m-xylene Phosphorus trichloride Tetrahydrofuran Ethyl acetate Dichloromethane Magnesium Lithium

Preparation Products

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View Lastest Price from (XYL)2P(O)H manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
(XYL)2P(O)H 187344-92-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 mt
Release date
2024-11-28
Henan Aochuang Chemical Co.,Ltd.
Product
Bis(3,5-dimethylphenyl)phosphine oxide 187344-92-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
XINXIANG RUNYU MATERIAL CO., LTD.
Product
Bis(3,5-dimethylphenyl)phosphine Oxide 187344-92-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
300KG
Release date
2024-02-20

187344-92-9, (XYL)2P(O)HRelated Search:

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  • 1-[(3,5-diMethylphenyl)phosphoryl]-3,5-diMethylbenzene
  • (XYL)2P(O)H
  • BIS(3,5-DIMETHYLPHENYL)PHOSPHINE OXIDE
  • Bis(3,5-dimethylphenyl)phosphine oxide ,97%
  • Bis(3,5-diMethylphenyl)phosphi
  • Phosphine oxide,bis(3,5-diMethylphenyl)-
  • bis(3,5-dimethylphenyl)-oxophosphanium
  • Bis(3,5-dimethylphenyl)phosphineOxide&gt
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  • 187344-92-9