ETHYL 3-METHYL-4-OXOCROTONATE

Product Name: ETHYL 3-METHYL-4-OXOCROTONATE
CAS No.: 62054-49-3
Chemical Name: ETHYL 3-METHYL-4-OXOCROTONATE
Synonyms: ethyl trans-γ-oxosenecioate;ETHYL 3-METHYL-4-OXOCROTOTE;Tretinoin Related Compound 4;ETHYL 3-METHYL-4-OXOCROTONATE;ETHYL TRANS-GAMMA-OXOSENECIOATE;Ethyl trans-3-Methyl-4-oxocrotonate;(E)-ethyl 3-Methyl-4-oxobut-2-enoate;Ethyl (E)-4-oxo-3-methyl-2-butenoate;Ethyl (E)-3-Methyl-4-oxo-2-butenoate;Ethyl (2E)-3-Methyl-4-oxobut-2-enoate
CBNumber: CB2297260
Molecular Formula: C7H10O3
Formula Weight: 142.15
MOL File: 62054-49-3.mol

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ETHYL 3-METHYL-4-OXOCROTONATE Property

Boiling point:: 195-202 °C(lit.)
Density: 1.044 g/mL at 20 °C(lit.)
refractive index: n20/D 1.461
Flash point:: 109 °C
storage temp.: 2-8°C
solubility: Chloroform, Ether, Ethyl Acetate, Methanol
form: Oil
color: Clear Colourless to Light Yellow
BRN: 1704098

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 23-24/25-36-26
WGK Germany: 3
F: 10
HS Code: 2918300090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 68259
Product name: Ethyl 3-methyl-4-oxocrotonate
Purity: ≥97.0% (GC)
Packaging: 50ml
Price: $323
Updated: 2025/07/31

TRC

Product number: E921985
Product name: Ethyltrans-3-Methyl-4-oxocrotonate
Packaging: 1g
Price: $65
Updated: 2021/12/16

TRC

Product number: E921985
Product name: Ethyltrans-3-Methyl-4-oxocrotonate
Packaging: 25g
Price: $475
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029687
Product name: ETHYL 3-METHYL-4-OXOCROTONATE
Purity: 95.00%
Packaging: 100MG
Price: $750.75
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029687
Product name: ETHYL 3-METHYL-4-OXOCROTONATE
Purity: 95.00%
Packaging: 1G
Price: $1963.5
Updated: 2021/12/16

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ETHYL 3-METHYL-4-OXOCROTONATE Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Uses

Derivative of monoenoic and trienoic analogs of Sorbic Acid with antifungal activity.

Synthesis

65527-85-7

62054-49-3

General procedure for the synthesis of ethyl 3-formyl-2-butenoate from ethyl (E)-4-hydroxy-3-methylbut-2-enoate: to a vigorously stirred solution of ethyl (E)-4-hydroxy-3-methylbut-2-enoate (9.37 g, 65 mmol) in dichloromethane (1.3 L) was added activated manganese dioxide powder (56.5 g, 650 mmol). The resulting suspension was stirred at room temperature for 1 hour and then filtered through a diatomaceous earth pad. The filtrate was evaporated to give pure ethyl 3-formyl-2-butenoate as a yellow oil. Yield: 7.66 g (92%); Thin Layer Chromatography (Spreading Agent D) Rf Value: 0.35; IR Spectra (pure sample, cm-1 ): 2829, 2740, 1718, 1660; GC-MS (electron bombardment, 20 eV): retention time = 4.82 min, mass-to-charge ratio (relative abundance): 142 (4, [M]+), 114 (15, [M- CO]+), 97 (100, [M-OCH2CH3]+), 96 (100, [M-CH3CH2OH]+); 1H nuclear magnetic resonance (CDCl3, δ): 9.54 (s, 1H), 6.49 (q, 1H, unresolved), 4.26 (q, 2H, J=6.8 Hz), 2.15 (d, 3H, J=1.2 Hz), and 1.33 (t, 3H, J=7.2Hz); 13C NMR (CDCl3, δ): 194.8, 165.7, 150.6, 135.8, 61.3, 14.4, 11.0.

References

[1] European Journal of Medicinal Chemistry, 2011, vol. 46, # 2, p. 721 - 737
[2] Synthesis, 1983, # 4, p. 297 - 300
[3] Journal of Organic Chemistry, 1986, vol. 51, # 2, p. 256 - 258

ETHYL 3-METHYL-4-OXOCROTONATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 3-METHYL-4-OXOCROTONATE Suppliers

Canada 1 China 74 Europe 1 Germany 1 India 2 Switzerland 1 United Kingdom 4 United States 11 Global 95

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View Lastest Price from ETHYL 3-METHYL-4-OXOCROTONATE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: ETHYL 3-METHYL-4-OXOCROTONATE 62054-49-3
Price: US $0.10/KG
Min. Order: 0.1KG
Purity: 98%HPLC
Supply Ability: 200tons
Release date: 2025-08-15

Hebei Chuanghai Biotechnology Co., Ltd

Product: ETHYL 3-METHYL-4-OXOCROTONATE 62054-49-3
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 mt
Release date: 2024-11-28

Career Henan Chemical Co

Product: ETHYL 3-METHYL-4-OXOCROTONATE 62054-49-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98% HPCL
Supply Ability: 10t
Release date: 2019-12-20

62054-49-3, ETHYL 3-METHYL-4-OXOCROTONATERelated Search:

TETRAETHYL ETHYLENETETRACARBOXYLATE ETHYL 3-METHYL-4-OXOCROTONATE TRIETHYL ACONITATE 2-CARBETHOXY-5,7-DIHYDROXY-4'-METHOXYISOFLAVONE DIETHYL DICYANOFUMARATE, 97 TRIALLYL ACONITATE ETHYL 2-(1-ALLYL-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDEN)ACETATE 3-HYDROXY-2-OXO-5,6,7,8-TETRAHYDRO-2H-PYRANO[3,2-B]PYRIDINE-4-CARBOXYLIC ACID ETHYL ESTER AKOS BC-1761 AKOS BBS-00006067 AKOS BBS-00006066 AKOS BBS-00006069 1-Propene-1,2,3-tricarboxylic acid, trihexyl ester 2-(TERT-BUTYL) 1,1-DIETHYL 1,1,2-ETHYLENETRICARBOXYLATE ETHYL 2-[1-(3,4-DICHLOROBENZYL)-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDEN]ACETATE RARECHEM AL BE 1458 AKOS BBS-00006068 AKOS BBS-00006065

ETHYL TRANS-3-METHYL-4-OXO-2-BUTENOATE

ETHYL TRANS-GAMMA-OXOSENECIOATE

ETHYL 3-METHYL-4-OXOCROTONATE

ethyl trans-γ-oxosenecioate

Ethyl trans-γ-oxosenecioate, Ethyl trans-3-methyl-4-oxo-2-butenoate

(E)-3-Methyl-4-oxo-2-butenoic Acid Ethyl Ester

3-Methyl-fuMaraldehydic Acid Ethyl Ester

Ethyl (2E)-3-Methyl-4-oxobut-2-enoate

Ethyl trans-3-Methyl-4-oxocrotonate

(E)-ethyl 3-Methyl-4-oxobut-2-enoate

Ethyl 3-Methyl-4-oxocrotonate >=97.0% (GC)

Ethyl (E)-4-oxo-3-methyl-2-butenoate

ETHYL 3-METHYL-4-OXOCROTOTE

Tretinoin Related Compound 4

2-Butenoic acid, 3-methyl-4-oxo-, ethyl ester, (2E)-

Ethyl (2E)-3-methyl-4-oxo-2-butenoate

Ethyl (E)-3-Methyl-4-oxo-2-butenoate

Ethyl 3-methyl-4-oxocrotonate(cis- and trans- mixture)

(E)-Ethyl 3-methyl-4-oxobut-2-enoate - [E72512]

62054-49-3

Building Blocks

Carbonyl Compounds

C7

Organic Building Blocks

Aldehydes

Aliphatics

Intermediates