TCS HDAC6 20b
- Product Name
- TCS HDAC6 20b
- CAS No.
- 956154-63-5
- Chemical Name
- TCS HDAC6 20b
- Synonyms
- TCS HDAC6 20b;DQZMLPMCOMRJOR-MOVGKWKRSA-N;S-[(6S)-7-(1-adamantylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]-7-oxoheptyl] 2-methylpropanethioate;2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester;Propanethioic acid, 2-methyl-, S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester
- CBNumber
- CB23037557
- Molecular Formula
- C26H44N2O4S
- Formula Weight
- 480.7
- MOL File
- 956154-63-5.mol
TCS HDAC6 20b Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- White Oily foam
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 14977
- Product name
- TCS HDAC6 20b
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 14977
- Product name
- TCS HDAC6 20b
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $145
- Updated
- 2024/03/01
- Product number
- 4805
- Product name
- TCSHDAC620b
- Purity
- ≥98%(HPLC)
- Packaging
- 10
- Price
- $224
- Updated
- 2021/12/16
- Product number
- 256885
- Product name
- TCS HDAC6 20b
- Packaging
- 10mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- T012700
- Product name
- TCSHDAC620b
- Packaging
- 25mg
- Price
- $1260
- Updated
- 2021/12/16
TCS HDAC6 20b Chemical Properties,Usage,Production
Description
TCS HDAC6 20b is an inhibitor of histone deacetylase 6 (HDAC6) that inhibits the growth of HCT116 cells synergistically when used at a concentration of 5 μM in combination with paclitaxel , but it has no activity on cell growth in HCT116 cells when used alone. It inhibits cell growth of α-positive MCF-7 breast cancer cells treated with estrogen but not untreated cells.
Uses
TCS HDAC6 20b is a histone deacetylase 6 (HDAC6)-selective inhibitor.
References
[1]. suzuki t, kouketsu a, itoh y, et al. highly potent and selective histone deacetylase 6 inhibitors designed based on a small-molecular substrate. j med chem, 2006, 49(16): 4809-4812.
[2]. itoh y, suzuki t, kouketsu a, et al. design, synthesis, structure--selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors. j med chem, 2007, 50(22): 5425-5438.
TCS HDAC6 20b Preparation Products And Raw materials
Raw materials
Preparation Products
TCS HDAC6 20b Suppliers
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