ChemicalBook > CAS DataBase List > Tigloylgomisin H

Tigloylgomisin H

Product Name: Tigloylgomisin H
CAS No.: 66069-55-4
Chemical Name: Tigloylgomisin H
Synonyms: Tigloylgomisin H;Crotonyl gomisin H;Tigloylgomisin H, 10 mM in DMSO;inhibit,Inhibitor,Tigloylgomisin H;2-Butenoic acid, 2-methyl-, (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester, (2E)-
CBNumber: CB23037562
Molecular Formula: C28H36O8
Formula Weight: 500.59
MOL File: 66069-55-4.mol

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Tigloylgomisin H Property

Boiling point:: 656.3±55.0 °C(Predicted)
Density: 1.144±0.06 g/cm3(Predicted)
pka: 14.56±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0100133
Product name: TigloylgomisinH
Packaging: 1mg
Price: $152
Updated: 2021/12/16

ChemScene

Product number: CS-0100133
Product name: TigloylgomisinH
Packaging: 5mg
Price: $457
Updated: 2021/12/16

Crysdot

Product number: CD32000684
Product name: TigloylgomisinH
Purity: 95+%
Packaging: 5mg
Price: $802
Updated: 2021/12/16

Arctom

Product number: CFN96618
Product name: TigloylgomisinH
Purity: ≥98%
Packaging: 5mg
Price: $318
Updated: 2021/12/16

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Tigloylgomisin H Chemical Properties,Usage,Production

Uses

Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis, can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent[1].

References

[1] Lee SB, et al. Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. Planta Med. 2009 Oct;75(12):1314-8. DOI:10.1055/s-0029-1185685
[2] Lee SB, et al. Induction of the phase II detoxification enzyme NQO1 in hepatocarcinoma cells by lignans from the fruit of Schisandra chinensis through nuclear accumulation of Nrf2. Planta Med. 2009 Oct;75(12):1314-8.

Tigloylgomisin H Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Tigloylgomisin H manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Tigloylgomisin H 66069-55-4
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-24

66069-55-4, Tigloylgomisin HRelated Search:

Gomisin L2 (6S,7S,12aR)-5,6,7,8-Tetrahydro-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cyclooctene-1,7-diol GOMISING gomisin D Benzoylgomisin H Angeloylgomisin O Isogomisin O Angeloylgomisin H gomisin J Gomisin S (-)Gomisin L1 Angeloyl-(+)-gomisin K3 (5R)-6β,7β-Dimethyl-1,2,3,12-tetramethoxy-10,11-methylenedioxy(5,6,7,8-tetrahydrodibenzo[a,c]cyclooctene)-5β,6α-diol 5-[(E)-2-methyl-2-butenoate] Angeloylgomisin P Angeloyl O iso gomisin Gomisin B Gomisin T Methylisogomisin O

Tigloylgomisin H

2-Butenoic acid, 2-methyl-, (6S,7S,12aR)-5,6,7,8-tetrahydro-7-hydroxy-2,3,10,11,12-pentamethoxy-6,7-dimethyldibenzo[a,c]cycloocten-1-yl ester, (2E)-

inhibit,Inhibitor,Tigloylgomisin H

Crotonyl gomisin H

Tigloylgomisin H, 10 mM in DMSO

66069-55-4