2-(2-AMINOPHENYL)PROPAN-2-OL
- Product Name
- 2-(2-AMINOPHENYL)PROPAN-2-OL
- CAS No.
- 15833-00-8
- Chemical Name
- 2-(2-AMINOPHENYL)PROPAN-2-OL
- Synonyms
- Nsc76547;2-(2-AMINOPHENYL)PROPAN-2-OL;o-aminophenyldimethylcarbinol;Benzenemethanol, 2-amino-α,α-dimethyl-;2-AMINO-ALPHA,ALPHA-DIMETHYLBENZYL ALCOHOL;o-Amino-alpha,alpha-dimethylbenzyl alcohol;alpha,alpha-Dimethyl-o-aminobenzyl alcohol;alhpa,alpha-Dimethyl-2-aminobenzyl alcohol;2-Amino-alpha,alpha-dimethylbenzenemethanol;benzenemethanol, 2-amino-alpha,alpha-dimethyl-
- CBNumber
- CB2305071
- Molecular Formula
- C9H13NO
- Formula Weight
- 151.21
- MOL File
- 15833-00-8.mol
2-(2-AMINOPHENYL)PROPAN-2-OL Property
- Boiling point:
- 289℃
- Density
- 1.084
- Flash point:
- 129℃
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 14.35±0.29(Predicted)
- Appearance
- Colorless to light yellow Viscous Liquid
Safety
- HazardClass
- IRRITANT
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A615733
- Product name
- 2-(2-Aminophenyl)propan-2-ol
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- FA66431
- Product name
- 2-Amino-alpha,alpha-dimethylbenzyl alcohol
- Packaging
- 250mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FA66431
- Product name
- 2-Amino-alpha,alpha-dimethylbenzyl alcohol
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FA66431
- Product name
- 2-Amino-alpha,alpha-dimethylbenzyl alcohol
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- FA66431
- Product name
- 2-Amino-alpha,alpha-dimethylbenzyl alcohol
- Packaging
- 2g
- Price
- $200
- Updated
- 2021/12/16
2-(2-AMINOPHENYL)PROPAN-2-OL Chemical Properties,Usage,Production
Synthesis
75-16-1
551-93-9
15833-00-8
GENERAL STEPS: 1-(2-aminophenyl)ethanone (1.50 g, 11.1 mmol) was dissolved in tetrahydrofuran (11 mL) under argon protection and cooled at 0 °C. Subsequently, methylmagnesium bromide (1.0 mol/L tetrahydrofuran solution, 11.1 mL, 11.1 mmol) was added slowly. After addition, the reaction mixture was gradually warmed to room temperature and stirred. Upon completion of the reaction, the reaction was carefully quenched with saturated aqueous ammonium chloride solution. The reaction mixture was extracted with ethyl acetate (3 x 20 mL), the organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product obtained was a brown oil, which was purified by fast column chromatography to give 2-(2-aminophenyl)propan-2-ol as a light-colored oil (1.20 g, 72% yield).LC-MS analysis showed a retention time of 0.24 min, and m/z 134 ([M-OH]-) was observed in ESI+ mode.1H NMR (400 MHz, chloroform-d) δ ( ppm): 7.15 (d, 1H), 7.06 (t, 1H), 6.72 (t, 1H), 6.65 (d, 1H), 3.65 (br s, 1H), 1.67 (s, 6H).
References
[1] Patent: WO2018/17490, 2018, A1. Location in patent: Paragraph 0163; 0164
[2] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 1, p. 189 - 192
[3] Organic and Biomolecular Chemistry, 2015, vol. 13, # 47, p. 11486 - 11491
2-(2-AMINOPHENYL)PROPAN-2-OL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(2-AMINOPHENYL)PROPAN-2-OL manufacturers
- Product
- 2-(2-Aminophenyl)propan-2-ol 15833-00-8
- Price
- US $0.00-0.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- 500kgs/month
- Release date
- 2021-11-20