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2'-O-Methyl-4-thiouridine

Product Name
2'-O-Methyl-4-thiouridine
CAS No.
34218-80-9
Chemical Name
2'-O-Methyl-4-thiouridine
Synonyms
2'-O-Methyl-4-thiouridine;2’-O-Methyl-4-thiouridine;Uridine, 2'-O-methyl-4-thio- (8CI);1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
CBNumber
CB23051687
Molecular Formula
C10H14N2O5S
Formula Weight
274.29
MOL File
34218-80-9.mol
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2'-O-Methyl-4-thiouridine Property

form 
Solid
color 
Yellow to brown
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Hazard and Precautionary Statements (GHS)

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2'-O-Methyl-4-thiouridine Chemical Properties,Usage,Production

Uses

2’-O-Methyl-4-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

2'-O-Methyl-4-thiouridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2'-O-Methyl-4-thiouridine Suppliers

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34218-80-9, 2'-O-Methyl-4-thiouridineRelated Search:


  • 2'-O-Methyl-4-thiouridine
  • Uridine, 2'-O-methyl-4-thio- (8CI)
  • 2’-O-Methyl-4-thiouridine
  • 1-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-4-thioxo-3,4-dihydropyrimidin-2(1H)-one
  • 34218-80-9