ChemicalBook > CAS DataBase List > [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
- Product Name
- [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
- CAS No.
- 1446282-35-4
- Chemical Name
- [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
- Synonyms
- C6-Bis-phosphoramidic acid diethyl ester;[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
- CBNumber
- CB23062263
- Molecular Formula
- C14H34N2O6P2
- Formula Weight
- 388.38
- MOL File
- 1446282-35-4.mol
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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Property
- Boiling point:
- 442.2±55.0 °C(Predicted)
- Density
- 1.106±0.06 g/cm3(Predicted)
- pka
- 2.06±0.70(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-21723
- Product name
- [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
- Purity
- 96%
- Packaging
- 250mg
- Price
- $260
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-21723
- Product name
- [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
- Purity
- 96%
- Packaging
- 500mg
- Price
- $380
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-21723
- Product name
- [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
- Purity
- 96%
- Packaging
- 1g
- Price
- $580
- Updated
- 2021/12/16
SynQuest Laboratories
- Product number
- 8177-1-32
- Product name
- [6-(Diethoxyphosphorylamino)hexyl]phosphoramidic acid diethyl ester
- Packaging
- 250mg
- Price
- $600
- Updated
- 2021/12/16
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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Chemical Properties,Usage,Production
Biological Activity
C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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