[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester

Product Name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
CAS No.: 1446282-35-4
Chemical Name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
Synonyms: C6-Bis-phosphoramidic acid diethyl ester;[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester
CBNumber: CB23062263
Molecular Formula: C14H34N2O6P2
Formula Weight: 388.38
MOL File: 1446282-35-4.mol

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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Property

Boiling point:: 442.2±55.0 °C(Predicted)
Density: 1.106±0.06 g/cm3(Predicted)
pka: 2.06±0.70(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-21723
Product name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
Purity: 96%
Packaging: 250mg
Price: $260
Updated: 2021/12/16

BroadPharm

Product number: BP-21723
Product name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
Purity: 96%
Packaging: 500mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-21723
Product name: [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidicaciddiethylester
Purity: 96%
Packaging: 1g
Price: $580
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8177-1-32
Product name: [6-(Diethoxyphosphorylamino)hexyl]phosphoramidic acid diethyl ester
Packaging: 250mg
Price: $600
Updated: 2021/12/16

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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Chemical Properties,Usage,Production

Biological Activity

C6-Bis-phosphoramidic acid diethyl ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester Suppliers

China 10 India 1 United Kingdom 1 United States 4 Global 16

Apollo Scientific Ltd.

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Email: sales@apolloscientific.co.uk
Country: United Kingdom
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1446282-35-4, [6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl esterRelated Search:

[4-(Diethoxy-phosphorylamino)-butyl]-phosphoramidic acid diethyl ester [2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester

[6-(Diethoxy-phosphorylamino)-hexyl]-phosphoramidic acid diethyl ester

C6-Bis-phosphoramidic acid diethyl ester

1446282-35-4

C14H34N2O6P2