Physical state Shipping Condition
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N-TETRADECYLPHOSPHONIC ACID

Physical state Shipping Condition
Product Name
N-TETRADECYLPHOSPHONIC ACID
CAS No.
4671-75-4
Chemical Name
N-TETRADECYLPHOSPHONIC ACID
Synonyms
TDPA;TETRADECYL PHOSPHONATE;myristylphosphonic acid;tetradecyl-phosphonicaci;tetradecanephosphonicacid;TETRADECYLPHOSPHONIC ACID;N-TETRADECYLPHOSPHONIC ACID;1-tetradecylphosphonic acid;1-TETRADECANEPHOSPHONIC ACID;P-tetradecyl-Phosphonic acid
CBNumber
CB2309695
Molecular Formula
C14H31O3P
Formula Weight
278.37
MOL File
4671-75-4.mol
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N-TETRADECYLPHOSPHONIC ACID Property

Melting point:
96-98°C
Boiling point:
175.8°C
Density 
0.998±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
≥27.8 mg/mL in ETOH; insoluble in H2O; ≥2.27 mg/mL in DMSO with gentle warming and ultrasonic
pka
2.65±0.10(Predicted)
form 
Powder
color 
white to off-white
Water Solubility 
Soluble in ethanol, dimethyl sulfoxide and dimethyl formamide. Partially soluble in water.
InChIKey
BVQJQTMSTANITJ-UHFFFAOYSA-N
CAS DataBase Reference
4671-75-4
EPA Substance Registry System
Phosphonic acid, tetradecyl- (4671-75-4)
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
2
RTECS 
TA0460000
TSCA 
Yes
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
736414
Product name
Tetradecylphosphonic acid
Purity
97%
Packaging
1g
Price
$113
Updated
2024/03/01
Sigma-Aldrich
Product number
736414
Product name
Tetradecylphosphonic acid
Purity
97%
Packaging
5g
Price
$331
Updated
2024/03/01
Sigma-Aldrich
Product number
736414
Product name
Tetradecylphosphonic acid
Purity
98%
Packaging
100G
Price
$1420
Updated
2023/06/20
TCI Chemical
Product number
T3183
Product name
Tetradecylphosphonic Acid
Purity
>98.0%(T)
Packaging
1g
Price
$87
Updated
2024/03/01
TCI Chemical
Product number
T3183
Product name
Tetradecylphosphonic Acid
Purity
>98.0%(T)
Packaging
5g
Price
$308
Updated
2024/03/01
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N-TETRADECYLPHOSPHONIC ACID Chemical Properties,Usage,Production

Physical state

N-TETRADECYLPHOSPHONIC ACID is a white to off-white powder.    

Shipping Condition

Room Temperature; may vary elsewhere.

Uses

1-Tetradecylphosphonic acid is used to functionalize the surface of BaTiO3 nanoparticles.

Uses

TDPA can be used to cap copper nanoparticles to protect them from oxidation. It may also be used in the synthesis of cadmium sulfate (CdS) core, which can be used in the fabrication of cadmium selenium (CdSe)/CdS core quantum dots (QDs). It may also be coated on caesium lead bromide (CsPbBr3) perovskite quantum dots for the development of white light emitting diodes (wLED).

General Description

Tetradecylphosphonic acid forms a self-assembled monolayer (SAM) to functionalize a variety of nanoparticles.

Biological Activity

tetradecyl phosphonate is a pan-antagonist of lysophosphatidic acid 1 (lpa1), lpa2, and lpa3 receptors. the ic50 value for inhibition of lpa-induced calcium mobilization was 10 μm, 5.5 μm, and 3.1 μm, respectively. at a concentration of 10 μm, tetradecyl phosphonate activates a peroxisome proliferator-activated receptor γ reporter construct 4-fold when compared with the controls and partially inhibits autotaxin with an ic50 value of approximately 3 μm [1].lysophosphatidic acid (lpa), also known as autotaxin (atx), is a lipid signalling molecule formed by the hydrolysis of lysophosphatidyl choline by lysophospholipase d [2]. lpa signals through four different g protein-coupled receptors, named as lpa1/edg-2, lpa2/edg-4, lpa3/edg-7, and lpa4/gpr23 [3]. it has been reported that lpa was involved in activating peroxisome proliferator-activated receptor γ (pparγ) [4].

References

[1]. durgam g g, virag t, walker m d, et al. synthesis, structure activity relationships, and biological evaluation of fatty alcohol phosphates as lysophosphatidic acid receptor ligands, activators of pparγ, and inhibitors of autotaxin[j]. journal of medicinal chemistry, 2005, 48(15): 4919-4930.
[2]. tokumura a, majima e, kariya y, et al. identification of human plasma lysophospholipase d, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase[j]. journal of biological chemistry, 2002, 277(42): 39436-39442.
[3]. noguchi k, ishii s, shimizu t. identification of p2y9/gpr23 as a novel g protein-coupled receptor for lysophosphatidic acid, structurally distant from the edg family[j]. journal of biological chemistry, 2003, 278(28): 25600-25606.
[4]. mcintyre t m, pontsler a v, silva a r, et al. identification of an intracellular receptor for lysophosphatidic acid (lpa): lpa is a transcellular pparγ agonist[j]. proceedings of the national academy of sciences, 2003, 100(1): 131-136.

N-TETRADECYLPHOSPHONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-TETRADECYLPHOSPHONIC ACID manufacturers

Career Henan Chemical Co
Product
TDPA 4671-75-4
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2018-08-21

4671-75-4, N-TETRADECYLPHOSPHONIC ACIDRelated Search:


  • TDPA
  • TETRADECYL PHOSPHONATE
  • TETRADECYLPHOSPHONIC ACID
  • N-TETRADECYLPHOSPHONIC ACID
  • 1-TETRADECANEPHOSPHONIC ACID
  • tetradecanephosphonicacid
  • tetradecyl-phosphonicaci
  • n-Tetradecylphosphonicacid,min.97%
  • 1-tetradecylphosphonic acid
  • Tetradecylphosphonic acid, 98 %
  • n-Tetradecylphosphonic acid, min. 97%
  • n-Tetradecylphosphonicacid,98%
  • myristylphosphonic acid
  • P-tetradecyl-Phosphonic acid
  • n-Tetradecylphosphonic acid, min. 97% TDPA
  • Phosphonic acid, P-tetradecyl-
  • 4671-75-4
  • 111-11-7
  • CH3CH213POOH2
  • organic phosphonic acid