YHO-13351 (free base)

Product Name: YHO-13351 (free base)
CAS No.: 912288-64-3
Chemical Name: YHO-13351 (free base)
Synonyms: YHO-13351 (free base);YHO-13351 free base, 10 mM in DMSO;YHO13351 FREE BASE;YHO 13351 FREE BASE;Glycine, N,N-diethyl-, 1-[5-[(1Z)-2-cyano-2-(3,4-dimethoxyphenyl)ethenyl]-2-thienyl]-4-piperidinyl ester
CBNumber: CB23121137
Molecular Formula: C26H33N3O4S
Formula Weight: 483.62
MOL File: 912288-64-3.mol

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YHO-13351 (free base) Property

Boiling point:: 627.1±55.0 °C(Predicted)
Density: 1.22±0.1 g/cm3(Predicted)
pka: 8.24±0.25(Predicted)
form: Solid
color: Yellow to orange

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-5438
Product name: YHO-13351freebase
Purity: 98.10%
Packaging: 5mg
Price: $100
Updated: 2021/12/16

ChemScene

Product number: CS-5438
Product name: YHO-13351freebase
Purity: 98.10%
Packaging: 50mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-5438
Product name: YHO-13351freebase
Purity: 98.10%
Packaging: 100mg
Price: $750
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611614
Product name: YHO-13351 free base
Packaging: 100mg
Price: $765
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611614
Product name: YHO-13351 free base
Packaging: 250mg
Price: $1504.5
Updated: 2021/12/16

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YHO-13351 (free base) Chemical Properties,Usage,Production

Uses

YHO-13351 free base is the prodrug of YHO-13177, which is a potent and specific inhibitor of BCRP.

References

[1] Yamazaki R, et al. Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRP/ABCG2-mediated drug resistance in vitro and in vivo. Mol Cancer Ther. 2011 Jul;10(7):1252-63. DOI:10.1158/1535-7163.MCT-10-0874
[2] Shishido Y, et al. ABCG2 inhibitor YHO-13351 sensitizes cancer stem/initiating-like side population cells to irinotecan. Anticancer Res. 2013 Apr;33(4):1379-86. PMID:23564776

YHO-13351 (free base) Preparation Products And Raw materials

Raw materials

Preparation Products

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YHO-13351 (free base) Suppliers

China 21 United States 4 Global 25

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912288-64-3, YHO-13351 (free base)Related Search:

YHO-13177 YHO-13351

YHO13351 FREE BASE;YHO 13351 FREE BASE

YHO-13351 (free base)

Glycine, N,N-diethyl-, 1-[5-[(1Z)-2-cyano-2-(3,4-dimethoxyphenyl)ethenyl]-2-thienyl]-4-piperidinyl ester

YHO-13351 free base, 10 mM in DMSO

912288-64-3