M2I-1

Product Name: M2I-1
CAS No.: 312271-03-7
Chemical Name: M2I-1
Synonyms: M2I-1;M2I1;M2I 1;M2I-1;Mad2 inhibitor-1;M2I-1, 10 mM in DMSO;Mad2 inhibitor-1 (M2I-1);PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2;5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione;4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-
CBNumber: CB23128969
Molecular Formula: C19H24N4O4S
Formula Weight: 404.48
MOL File: 312271-03-7.mol

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M2I-1 Property

Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: slightly soluble
form: A crystalline solid
pka: 4.79±0.20(Predicted)
color: Yellow to orange

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 22297
Product name: M2I-1
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 22297
Product name: M2I-1
Purity: ≥98%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 22297
Product name: M2I-1
Purity: ≥98%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 22297
Product name: M2I-1
Purity: ≥98%
Packaging: 25mg
Price: $230
Updated: 2024/03/01

Ambeed

Product number: A566234
Product name: M2I-1
Purity: 98%
Packaging: 2mg
Price: $118
Updated: 2021/12/16

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M2I-1 Chemical Properties,Usage,Production

Uses

M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC)[1].

Biological Activity

Cell permeable: yes', 'Primary Target
Mad2', 'Reversible: yes

References

[1] Johanna Kastl et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem. Biol., 2015, 10 (7), pp 1661-1666. DOI:10.1021/acschembio.5b00121

M2I-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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M2I-1 Suppliers

China 77 United States 6 Global 83

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312271-03-7, M2I-1Related Search:

5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione

M2I1;M2I 1;M2I-1

M2I-1

Mad2 inhibitor-1 (M2I-1)

Mad2 inhibitor-1

4,6(1H,5H)-Pyrimidinedione, 5-[[4-[bis(2-methylpropyl)amino]-3-nitrophenyl]methylene]dihydro-2-thioxo-

PPI,M2I-1,M2I1,inhibit,M-2I-1,interaction,protein-protein,Cdc20,Inhibitor,Mad2

M2I-1, 10 mM in DMSO

312271-03-7

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