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Cariprazine D8

Product Name
Cariprazine D8
CAS No.
1308278-50-3
Chemical Name
Cariprazine D8
Synonyms
Cariprazine D8;[2H8]-Cariprazine;Cariprazine D8 (Piperazine-d8);Cariprazine-D8 solution
CBNumber
CB23129380
Molecular Formula
C21H32Cl2N4O
Formula Weight
427.41
MOL File
1308278-50-3.mol
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Cariprazine D8 Property

Melting point:
>198°C (dec.)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Off-White to Pale Beige
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Safety

WGK Germany 
WGK 2
Storage Class
3 - Flammable liquids
Hazard Classifications
Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Met. Corr. 1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H290May be corrosive to metals

H302Harmful if swallowed

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P234Keep only in original container.

P240Ground/bond container and receiving equipment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

A2B
Product number
AX33668
Product name
Cariprazine-d8
Packaging
2.5mg
Price
$326
Updated
2021/12/16
A2B
Product number
AX33668
Product name
Cariprazine-d8
Packaging
10mg
Price
$776
Updated
2021/12/16
A2B
Product number
AX33668
Product name
Cariprazine-d8
Packaging
25mg
Price
$1536
Updated
2021/12/16
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Cariprazine D8 Chemical Properties,Usage,Production

Uses

Cariprazine-d8 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

IC 50

D3 Receptor

References

[1] Seneca N, et al. Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-8. DOI:10.1007/s00213-011-2343-z

Cariprazine D8 Preparation Products And Raw materials

Raw materials

Preparation Products

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Cariprazine D8 Suppliers

China 7 India 4 United States 1 Global 12
Shanghai Champ Biopharmaceuticals Co., Ltd.
Tel
021-61537865 13585780846
Email
sales@champchem.com
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China
ProdList
361
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Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-037163312495,13303845143 13303845143
Fax
QQ3001379618
Email
3001379618@qq.com
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China
ProdList
10227
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BOC Sciences
Tel
+1-631-485-4226
Fax
1-631-614-7828
Email
inquiry@bocsci.com
Country
United States
ProdList
19552
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Manhag Testing Technology Co., Ltd
Tel
020-3846 2365 19110442770
Email
458677837@qq.com
Country
China
ProdList
7775
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Nanjing Shizhou Biology Technology Co.,Ltd
Tel
17301488900
Fax
025-85560043
Email
judy.xia@synzest.com
Country
China
ProdList
12582
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58
BePure (Beijing) Biotechnology Co.
Tel
58896805
Email
7993601name@qq.com
Country
CHINA
ProdList
6620
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58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
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58

1308278-50-3, Cariprazine D8Related Search:

Cariprazine Nsc175383 Cariprazine intermediate 2 Desmethyl Cariprazine Piperazine, 1-(2-chloroethyl)-4-(2,3-dichlorophenyl)- Urea, N,N'-bis[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]- Urea, N,N-dimethyl-N'-[trans-4-[2-[[(4-methylphenyl)sulfonyl]oxy]ethyl]cyclohexyl]- ethyl dimethylcarbamate 3,3-dimethyl-1-[(1r,4r)-4-(2-hydroxyethyl)cyclohexyl]urea Cyclohexaneethanol, 4-amino-, hydrochloride (1:1), trans-

  • Cariprazine D8
  • [2H8]-Cariprazine
  • Cariprazine D8 (Piperazine-d8)
  • Cariprazine-D<sub>8</sub> solution
  • 1308278-50-3