dBET1

ChemicalBook > CAS DataBase List > dBET1

Product Name: dBET1
CAS No.: 1799711-21-9
Chemical Name: dBET1
Synonyms: dBET1;CS-2706;DBET1;DBET-1 ;DBET 1;JQ1-Thalidomide conjugate;dBET1,inhibit,PROTACs,Epigenetic Reader Domain,Inhibitor,dBET 1,dBET-1;2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-;N-(4-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2 (6),4,7,10,12-pentaen-9-yl]acetamido}butyl)-2-{[2-( 2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-i soindol-4-yl]oxy}acetamide
CBNumber: CB23133361
Molecular Formula: C38H37ClN8O7S
Formula Weight: 785.27
MOL File: 1799711-21-9.mol

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dBET1 Property

Melting point:: 186 - 187°C
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 10.68±0.40(Predicted)
form: Solid
color: Pale Yellow
Stability:: Hygroscopic

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18044
Product name: dBET1
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 18044
Product name: dBET1
Purity: ≥98%
Packaging: 5mg
Price: $193
Updated: 2024/03/01

Cayman Chemical

Product number: 18044
Product name: dBET1
Purity: ≥98%
Packaging: 10mg
Price: $363
Updated: 2024/03/01

TRC

Product number: I120055
Product name: dBET1
Packaging: 2.5mg
Price: $855
Updated: 2021/12/16

TRC

Product number: I120055
Product name: dBET1
Packaging: 1mg
Price: $360
Updated: 2021/12/16

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dBET1 Chemical Properties,Usage,Production

Description

dBET1 is a PROTAC compound comprised of BET bromodomain antagonist (+)-JQ1 linked to a cereblon E3 ubiquitin ligase ligand.

Uses

dBET1 induces highly selective cereblon-dependent BET protein degradation in vitro and in vivo as well as delays leukemia progression in mice.

storage

Store at -20°C

dBET1 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from dBET1 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: dBET1 1799711-21-9
Price: US $0.00/mg
Min. Order: 1mg
Purity: 98%min
Supply Ability: 500mg
Release date: 2021-08-26

Career Henan Chemical Co

Product: dBET1 1799711-21-9
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-13

1799711-21-9, dBET1Related Search:

dBET1

DBET1;DBET-1 ;DBET 1

CS-2706

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[4-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]butyl]-2,3,9-trimethyl-, (6S)-

N-(4-{2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0,2,6]trideca-2 (6),4,7,10,12-pentaen-9-yl]acetamido}butyl)-2-{[2-( 2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-i soindol-4-yl]oxy}acetamide

2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)butyl)acetamide

dBET1,inhibit,PROTACs,Epigenetic Reader Domain,Inhibitor,dBET 1,dBET-1

JQ1-Thalidomide conjugate

1799711-21-9

C38H37ClN8O7S