(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

ChemicalBook > CAS DataBase List > (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide

Product Name: (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
CAS No.: 1384441-38-6
Chemical Name: (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide
Synonyms: O-Demethyl apremilast;Apremilast Impurity K;Apremilast O-Desmethyl;O-Desmethyl Apremilast;Apremilast impurity HS093311;Apremilast Impurity 4 (O-Desmethyl Apremilast);N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide;N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide;Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-;(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity
CBNumber: CB23145520
Molecular Formula: C21H22N2O7S
Formula Weight: 446.47
MOL File: 1384441-38-6.mol

Less

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Property

Boiling point:: 765.2±60.0 °C(Predicted)
Density: 1.450±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
form: A crystalline solid
pka: 9.80±0.31(Predicted)
Stability:: Hygroscopic

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

TRC

Product number: E892255
Product name: N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide
Packaging: 5mg
Price: $55
Updated: 2021/12/16

TRC

Product number: E892255
Product name: N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide
Packaging: 10mg
Price: $105
Updated: 2021/12/16

Less

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Chemical Properties,Usage,Production

Uses

N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide is a related compound of Apremilast (A729700), which is?an oral phosphodiesterase 4 inhibitor used for treating psoriatic arthritis. N-[2-[(1S)-1-(3-Ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide may be a useful compound for determining metabolic clearance of apremilast. Apremilast Impurity 7

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide Suppliers

China 40 India 2 United States 3 Global 45

Shenzhen ruikai de biotechnology co., ltd.

Tel: 0755-61348847 17820674378
Fax: 0755-21016893
Email: 2682116078@qq.com
Country: China
ProdList: 7844
Advantage: 58

Beijing Comparison Pharmaceutical Technology Co., Ltd

Tel: 010-52878169 15701683040
Email: sales@bjcomparison.com
Country: China
ProdList: 4701
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17993
Advantage: 56

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-58362220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
Country: China
ProdList: 7725
Advantage: 55

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9294
Advantage: 58

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3063
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55934
Advantage: 58

Shenzhen Botel Biotechnology Co. Ltd.

Tel: 0755-22202135 13316968096
Email: 1979313431@qq.com
Country: China
ProdList: 7898
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 2881290884@qq.com
Country: China
ProdList: 7506
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23556
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 17825480238
Fax: QQ 3008233717
Email: 3008233717@qq.com
Country: China
ProdList: 9843
Advantage: 12

Tianjin shijia biomedical technology co., LTD

Tel: 15022261580;411316762
Email: tjshj1212@163.com
Country: China
ProdList: 2347
Advantage: 58

Jinan blalong chemical co. LTD

Tel: 2710913286@.com
Email: 1513643261@qq.com
Country: China
ProdList: 14253
Advantage: 58

Shenzhen Hengfeng Wanda Pharmaceutical Technology Co., Ltd

Tel: 755-22677922-801 18126518403
Fax: 518109
Email: 2851922760@qq.com
Country: China
ProdList: 5043
Advantage: 58

SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD

Tel: 0755-0755-0755-83725350 13380397412
Fax: 0755-28094224
Email: 3001280422@qq.com
Country: China
ProdList: 9939
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing1@energy-chemical.com
Country: China
ProdList: 44843
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4576
Advantage: 58

Hubei Ruinuo Pharmaceutical Technology Co., Ltd

Tel: 0714-5316360 13165688766
Fax: 0714-5316360
Email: 123456789@qq.com
Country: China
ProdList: 5001
Advantage: 58

Guangzhou Juntang Technology Co., Ltd

Tel: 020-36607679 13502246435
Email: sales@dmstandards.com
Country: China
ProdList: 10951
Advantage: 58

Beijing Fuchen Technology Co., Ltd

Tel: 18732139959
Email: 38552532@qq.com
Country: China
ProdList: 10
Advantage: 58

Beijing Fuchen Technology Co., Ltd

Tel: 15652759959
Email: 623245911@qq.com
Country: China
ProdList: 461
Advantage: 58

Foshan Treasure Biotechnology Co., Ltd

Tel: 0757-85921206 18520245316
Email: 2329783215@qq.com
Country: China
ProdList: 12664
Advantage: 58

Molcoo Chemicals Inc.

Tel: 18627923403 18274848843
Email: 3001006472@qq.com
Country: China
ProdList: 8665
Advantage: 58

Hunan Zengda Biological Technology Co., LTD

Tel: 18711085600
Email: 1652923704@qq.com
Country: China
ProdList: 4583
Advantage: 58

Shenzhen Roark Pharma-Tec Co., Ltd.

Tel: 13128912434
Email: 2880126944@qq.com
Country: China
ProdList: 2580
Advantage: 58

Changzhou Bojia Biomedical Technology Co., Ltd.

Tel: 2122619822
Email: czbjpharma@126.com
Country: China
ProdList: 18488
Advantage: 58

Shanghai YuZn Pharm. Technology Co.,Ltd.

Tel: 15921286451; 15921286451
Email: 2010681527@qq.com
Country: China
ProdList: 5067
Advantage: 58

HX Pharmaceutical technology co., LTD

Tel: 15671363360
Email: 494267389@qq.com
Country: China
ProdList: 2320
Advantage: 58

Tan-Mo Technology Co., Ltd.

Tel: 19850211281
Email: qiann@gbw-china.com
Country: China
ProdList: 1980
Advantage: 58

Shanghai Yifei Biotechnology Co. , Ltd.

Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Country: China
ProdList: 8740
Advantage: 58

Hubei De'ao Chemical Research Pharmaceutical Technology Co., Ltd

Tel: 18502726233
Email: 3641133981@qq.com
Country: China
ProdList: 9341
Advantage: 58

Hangzhou Bingochem Co., Ltd.

Tel: 0571-87632989
Email: sales@bingochem.com
Country: China
ProdList: 21673
Advantage: 58

Baoji Didu Pharmaceutical and Chemical Co., Ltd

Tel: 029-61856358 15829046862
Email: 1035@dideu.com
Country: China
ProdList: 10011
Advantage: 58

Shenzhen Xingyue Biotechnology Co., Ltd

Tel: 18124513697; 18124513697
Fax: 18822823697
Email: jjj18822823697@163.com
Country: China
ProdList: 1408
Advantage: 58

Nantong Hanfang Biotechnology Co. , Ltd.

Tel: 3674309880
Email: hanfangpharma@126.com
Country: China
ProdList: 30968
Advantage: 58

Hubei Moco Chemical Co., Ltd.

Tel: 18627753421 18627756402
Fax: QQ：3001051413
Email: 3001009495@qq.com
Country: China
ProdList: 10450
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.com
Country: China
ProdList: 24246
Advantage: 58

China National Standard Pharmaceutical Corporation Limited

Tel: +8615391658522
Email: overseasales@yongstandards.com
Country: China
ProdList: 11927
Advantage: 58

LEAP CHEM CO., LTD.

Tel: +86-852-30606658
Email: market18@leapchem.com
Country: China
ProdList: 24738
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6846
Advantage: 58

1384441-38-6, (S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamideRelated Search:

O-Desmethyl Apremilast

N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide

Apremilast impurity HS093311

Apremilast Impurity K

Apremilast Impurity 4 (O-Desmethyl Apremilast)

Acetamide,N-[2-[(1S)-1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl-

N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3- dioxoisoindolin-4-yl)acetamide

(S)-N-(2-(1-(3-ethoxy-4-hydroxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-4-yl)acetamide,Apremilast Impurity

O-Demethyl apremilast

Apremilast O-Desmethyl

1384441-38-6