TAK-659

Product Name: TAK-659
CAS No.: 1312691-33-0
Chemical Name: TAK-659
Synonyms: TAK-659;TAK-659-01;Mivavotinib;Tak-659 free base;MIVAVOTINIB;TAK 659;TAK659;TAK-659 free base(Mivavotinib);6-((1R,2S)-2-Aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridin-3(2H)-one;3H-Pyrrolo[3,4-c]pyridin-3-one, 6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-1,2-dihydro-4-(1-methyl-1H-pyrazol-4-yl)-
CBNumber: CB23145555
Molecular Formula: C17H21FN6O
Formula Weight: 344.39
MOL File: 1312691-33-0.mol

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TAK-659 Property

Boiling point:: 661.7±55.0 °C(Predicted)
Density: 1.58±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 10.90±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb611303
Product name: TAK-659 free base
Packaging: 100mg
Price: $765
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611303
Product name: TAK-659 free base
Packaging: 250mg
Price: $1356.6
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611303
Product name: TAK-659 free base
Packaging: 1g
Price: $2691.1
Updated: 2021/12/16

DC Chemicals

Product number: DC21280
Product name: TAK-659freebase(Mivavotinib)
Purity: >98%
Packaging: 100mg
Price: $500
Updated: 2021/12/16

DC Chemicals

Product number: DC21280
Product name: TAK-659freebase(Mivavotinib)
Purity: >98%
Packaging: 1g
Price: $1800
Updated: 2021/12/16

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TAK-659 Chemical Properties,Usage,Production

Uses

Mivavotinib is employed in the discovery of Lanraplenib, a tyrosine kinase inhibitor for autoimmune diseases.

in vivo

TAK-659 (100 mg/kg/day; p.o.; for 10 days) treatment totally abrogates splenomegaly and tumor development in LMP2A/MYC mice in both pretumor and tumor cell transfer experiments^[4].
TAK-659 treatment kills tumor cells, but not host cells within the spleen and tumors^[4].
TAK-659 treatment abrogates metastasis of tumor cells into bone marrow^[4].

Animal Model:	LMP2A/MYC double transgenic mice^[4]
Dosage:	100 mg/kg/day
Administration:	Oral gavage; for 10 days
Result:	Inhibited LMP2A-induced tumor cell survival in vivo.

TAK-659 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAK-659 Suppliers

China 31 United States 2 Global 33

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
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Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Twochem Co.Ltd

Tel: 021-021-58111628 15800915896
Fax: QQ 3285589261
Email: sales@twochem.com
Country: China
ProdList: 304
Advantage: 55

Chuzhou KeMail Chemical Technology Co., Ltd

Tel: 0550-5196001 15000891977
Fax: 0550-5196001
Email: wj520wjxby@126.com
Country: China
ProdList: 1944
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Shanghai Biopharmaleader Co., Ltd.

Tel: +86 18721201413
Fax: +86 (21) 5775-8967
Email: sales@biopharmaleader.com
Country: China
ProdList: 1720
Advantage: 58

Suzhou Ran enzyme Biotechnology Co., Ltd.

Tel: 0512-0512-62793604 18015430729
Fax: 0512-62793604
Email: 116667374@qq.com
Country: China
ProdList: 127
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3276
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

1312691-33-0, TAK-659Related Search:

TAK-659

6-((1R,2S)-2-Aminocyclohexylamino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[3,4-c]pyridin-3(2H)-one

Tak-659 free base

Mivavotinib

MIVAVOTINIB;TAK 659;TAK659

3H-Pyrrolo[3,4-c]pyridin-3-one, 6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-1,2-dihydro-4-(1-methyl-1H-pyrazol-4-yl)-

TAK-659 free base(Mivavotinib)

TAK-659-01

1312691-33-0