ChemicalBook > CAS DataBase List > DprE1-IN-2

DprE1-IN-2

Product Name
DprE1-IN-2
CAS No.
1615713-87-5
Chemical Name
DprE1-IN-2
Synonyms
CS-2339;DprE1-IN-2;DprE1-IN-25;DprE1 inhibitor 2;DprE1-IN-2, 10 mM in DMSO;DPRE1 INHIBITOR 2;DPRE1 IN 2;DprE1,antituberculosis,effect,DprE-1-IN-2,DprE1IN2,DprE1 IN 2,Bacterial,tuberculosis,Inhibitor,inhibit;1H-Pyrrolo[3,2-b]pyridine-3-carboxamide, 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-
CBNumber
CB23146608
Molecular Formula
C19H24N6O2
Formula Weight
368.43
MOL File
1615713-87-5.mol
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DprE1-IN-2 Property

Boiling point:
701.4±60.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 2mg/mL; DMSO: 2mg/mL; DMSO:PBS (pH 7.2) (1:4): 0.2mg/mL
form 
A crystalline solid
pka
12.81±0.46(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
21034
Product name
DprE1-IN2
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
21034
Product name
DprE1-IN2
Packaging
5mg
Price
$161
Updated
2024/03/01
Cayman Chemical
Product number
21034
Product name
DprE1-IN2
Packaging
10mg
Price
$283
Updated
2024/03/01
Cayman Chemical
Product number
21034
Product name
DprE1-IN2
Packaging
25mg
Price
$618
Updated
2024/03/01
ChemScene
Product number
CS-5834
Product name
DprE1-IN-2
Purity
99.55%
Packaging
5mg
Price
$120
Updated
2021/12/16
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DprE1-IN-2 Chemical Properties,Usage,Production

Uses

DprE1-IN-2 (compound 18) is a potent DprE1 inhibitor with an IC50 of 28 nM. DprE1-IN-2 has antituberculosis effect[1].

in vivo

DprE1-IN-2 (compound 18; oral; 100 mg/kg) has t1/2 of 0.9 hours and Cmax of 70 μM in BALB/c Mice[1].

Animal Model:BALB/c Mice[1]
Dosage:100 mg/kg
Administration:Oral
Result:Had t1/2 of 0.9 hours and Cmax of 70 μM.

References

[1] Shirude PS et al. Lead optimization of 1,4-azaindoles as antimycobacterial agents. J Med Chem. 2014 Jul 10;57(13):5728-37. DOI:10.1021/jm500571f

DprE1-IN-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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DprE1-IN-2 Suppliers

China 31 United States 7 Global 38
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
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65
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4660
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58

1615713-87-5, DprE1-IN-2Related Search:


  • DprE1-IN-2
  • CS-2339
  • DprE1 inhibitor 2
  • DPRE1 INHIBITOR 2;DPRE1 IN 2
  • DprE1-IN-25
  • 1H-Pyrrolo[3,2-b]pyridine-3-carboxamide, 1-[[6-(dimethylamino)-5-methyl-4-pyrimidinyl]methyl]-N-(2-hydroxyethyl)-6-methyl-
  • DprE1,antituberculosis,effect,DprE-1-IN-2,DprE1IN2,DprE1 IN 2,Bacterial,tuberculosis,Inhibitor,inhibit
  • DprE1-IN-2, 10 mM in DMSO
  • 1615713-87-5