ChemicalBook > CAS DataBase List > KPT-8602

KPT-8602

Product Name
KPT-8602
CAS No.
1642300-52-4
Chemical Name
KPT-8602
Synonyms
CS-2388;ATG-016;ONO-7706;KPT-8602;Eltanexor;KPT-8602 (KPT 8602;Eltanexor (KPT-8602;(E)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide;5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αE)-
CBNumber
CB23151727
Molecular Formula
C17H10F6N6O
Formula Weight
428.3
MOL File
1642300-52-4.mol
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KPT-8602 Property

Boiling point:
574.4±60.0 °C(Predicted)
Density 
1.57±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
13.06±0.50(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb611488
Product name
Eltanexor
Packaging
5mg
Price
$430.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611488
Product name
Eltanexor
Packaging
50mg
Price
$1149.2
Updated
2021/12/16
DC Chemicals
Product number
DC22589
Product name
Eltanexor
Purity
>98%
Packaging
50mg
Price
$760
Updated
2021/12/16
DC Chemicals
Product number
DC22589
Product name
Eltanexor
Purity
>98%
Packaging
5mg
Price
$208
Updated
2021/12/16
DC Chemicals
Product number
DC22589
Product name
Eltanexor
Purity
>98%
Packaging
10mg
Price
$280
Updated
2021/12/16
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KPT-8602 Chemical Properties,Usage,Production

Uses

(αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide is an exportin-1 inhibitor with anti-leukemic activity. Exportin-1 mediates nuclear trafficking of proteins. (αE)?-α-?[[3-?[3,?5-?bis(Trifluoromethyl)?phenyl]?-?1H-?1,?2,?4-?triazol-?1-?yl]?methylene]?-?5-pyrimidineacetamide can be used to develop treatments for acute lymphoblastic leukemia.

KPT-8602 Preparation Products And Raw materials

Raw materials

Preparation Products

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KPT-8602 Suppliers

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1642300-52-4, KPT-8602Related Search:


  • KPT-8602
  • Eltanexor (KPT-8602
  • CS-2388
  • KPT-8602 (KPT 8602
  • Eltanexor
  • 5-Pyrimidineacetamide, α-[[3-[3,5-bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]methylene]-, (αE)-
  • (E)-3-(3-(3,5-Bis(trifluoromethyl)phenyl)-1H-1,2,4-triazol-1-yl)-2-(pyrimidin-5-yl)acrylamide
  • ATG-016
  • ONO-7706
  • 1642300-52-4