5-Octyl L-glutamate Property

Melting point:

184.5-185.85 °C

Boiling point:

402.4±40.0 °C(Predicted)

Density 

1.057±0.06 g/cm3(Predicted)

solubility 

Methanol: 1 mg/ml (heated)

form 

A crystalline solid

pka

2.20±0.10(Predicted)

Hazard and Precautionary Statements (GHS)

5-Octyl L-glutamate Chemical Properties,Usage,Production

Description

While extracellular glutamic acid is an excitatory neurotransmitter, intracellular glutamic acid is an amino acid that serves numerous metabolic roles, including as a precursor for α-ketoglutarate. 5-Octyl L-glutamate, also known as 5-octyl ester glutamic acid, is a stable, cell-permeable molecule which generates free glutamic acid upon hydrolysis of the ester bond by cytoplasmic esterases. It may be used in experiments to increase levels of cytoplasmic glutamic acid. Alternatively, 5-octyl L-glutamate can be used to synthesize 5-octyl ester derivatives, including 5-octyl α-ketoglutarate, for delivery to cells.

Uses

5-Octyl L-Glutamate is a stable cell-permeable molecule which generates free glutamic acid upon hydrolysis of the ester bond by cytoplasmic esterase.