PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2

Product Name: PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2
CAS No.: 1926163-16-7
Chemical Name: PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2
Synonyms: Triptorelin-Leu-Arg-Pro-Gly-NH2;TRIPTORELIN-LEU-ARG-PRO-GLY AMIDE;(D-TRP6)-LHRH-LEU-ARG-PRO-GLY NH2;(D-Trp?)-LHRH-Leu-Arg-Pro-Gly amide;(D-TRP6)-LHRH-LEU-ARG-PRO-GLY AMIDE;PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2;(D-TRP6)-GONADOTROPIN-RELEASING HORMONE-LEU-ARG-PRO-GLY AMIDE;(D-TRP6)-LUTEINIZING HORMONE-RELEASING FACTOR-LEU-ARG-PRO-GLY AMIDE;(D-TRP6)-LUTEINIZING HORMONE-RELEASING HORMONE-LEU-ARG-PRO-GLY AMIDE;Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycyl-L-leucyl-L-arginyl-L-prolyl-
CBNumber: CB2316273
Molecular Formula: C83H115N25O17
Formula Weight: 1734.96
MOL File: Mol file

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PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2 Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: -15°C
pka: 9.82±0.15(Predicted)
Sequence: {Pyr}-His-Trp-Ser-Tyr-{d-Trp}-Leu-Arg-Pro-Gly-Leu-Arg-Pro-Gly-NH2

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: SHG0000333
Product name: [D-TRP6]-LH-RH-LEU-ARG-PRO-GLY-NH2
Purity: 95.00%
Packaging: 1MG
Price: $736.14
Updated: 2021/12/16

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PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2 Chemical Properties,Usage,Production

Uses

(D-Trp6)-LHRH-Leu-Arg-Pro-Gly amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1].

Biological Activity

Glp-His-Trp-Ser-Tyr-Trp-Leu-Arg-Pro-Gly-Leu-Arg-Pro-Gly-NH2 ([D-Trp6]-LH-RH-Leu-Arg-Pro-Gly-NH2) is a GnRH (gonadotropin-releasing hormone) agonist, triptorelin. GnRH (Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2), which is also referred as LHRH (luteinizing hormone-releasing hormone) or gonadorelin, is crucial for mammalian reproduction and is released from hypothalamic neurons. It is responsible for the secretion of gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary glands. Mutations in GnRH are associated with normosmic congenital hypogonadotropic hypogonadism. Triptorelin is used for the treatment of hormone-associated prostate and breast cancers, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization.

References

[1] Birnbaum S, et al. Peptide screening. Current Opinion in Biotechnology, 1992, 3(1): 49-54.

PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2 Preparation Products And Raw materials

Raw materials

Preparation Products

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PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2 Suppliers

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1926163-16-7, PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2Related Search:

Triptorelin

PYR-HIS-TRP-SER-TYR-D-TRP-LEU-ARG-PRO-GLY-LEU-ARG-PRO-GLY-NH2

TRIPTORELIN-LEU-ARG-PRO-GLY AMIDE

(D-TRP6)-LUTEINIZING HORMONE-RELEASING HORMONE-LEU-ARG-PRO-GLY AMIDE

(D-TRP6)-GONADOTROPIN-RELEASING HORMONE-LEU-ARG-PRO-GLY AMIDE

(D-TRP6)-LUTEINIZING HORMONE-RELEASING FACTOR-LEU-ARG-PRO-GLY AMIDE

(D-TRP6)-LHRH-LEU-ARG-PRO-GLY AMIDE

(D-TRP6)-LHRH-LEU-ARG-PRO-GLY NH2

Triptorelin-Leu-Arg-Pro-Gly-NH2

Glycinamide, 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-tryptophyl-L-leucyl-L-arginyl-L-prolylglycyl-L-leucyl-L-arginyl-L-prolyl-

(D-Trp?)-LHRH-Leu-Arg-Pro-Gly amide

1926163-16-7