ChemicalBook > CAS DataBase List > (S)-Equol

(S)-Equol

Product Name
(S)-Equol
CAS No.
531-95-3
Chemical Name
(S)-Equol
Synonyms
Equol;(S)-EQUOL;R,S-EQUOL;S,R-equol;(3S)-Equol;(-)-(S)-EQUOL;Equol USP/EP/BP;S-Equol S Equol;EQUOL, (+/-)-(SH);(S)-Equol,99%e.e.
CBNumber
CB2317528
Molecular Formula
C15H14O3
Formula Weight
242.27
MOL File
531-95-3.mol
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(S)-Equol Property

Melting point:
189-190°C
alpha 
D -21.5°
Boiling point:
312.25°C (rough estimate)
Density 
1.1914 (rough estimate)
refractive index 
1.5557 (estimate)
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Soluble), Ethanol (Slightly), Methanol (Slightly)
pka
9.94±0.40(Predicted)
form 
Solid
color 
White to Pale Yellow
CAS DataBase Reference
531-95-3(CAS DataBase Reference)
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Safety

WGK Germany 
3
F 
3-10
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
10010173
Product name
(S)-Equol
Purity
≥98%
Packaging
1mg
Price
$21
Updated
2024/03/01
Cayman Chemical
Product number
10010173
Product name
(S)-Equol
Purity
≥98%
Packaging
5mg
Price
$89
Updated
2024/03/01
Cayman Chemical
Product number
10010173
Product name
(S)-Equol
Purity
≥98%
Packaging
10mg
Price
$157
Updated
2024/03/01
Cayman Chemical
Product number
10010173
Product name
(S)-Equol
Purity
≥98%
Packaging
25mg
Price
$341
Updated
2024/03/01
Tocris
Product number
6158
Product name
(S)-Equol
Purity
≥98%(HPLC)
Packaging
10
Price
$122
Updated
2021/12/16
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(S)-Equol Chemical Properties,Usage,Production

Chemical Properties

White to Off-White Solid

Uses

Receptor; binding activity

Uses

A human urinary metabolite of Daidzein. It is also a natural estrogenic metabolite from soy isoflavones

Uses

serine protease

Uses

(S)-Equol and R-Equol are metabolites of the soy isoflavones Daidzein (D103500) and Genistein. Both have significant biological actions.

Definition

ChEBI: Equol is a member of hydroxyisoflavans.

Biological Activity

equol is an isoflavan produced by intestinal bacteria in response to soy isoflavone intake in human. it shows a wide range of activities including antioxidant activity, anti-inflammation activity and anticancer activity. it is reported that equol specifically binds to 5α-dht and has a modest affinity for recombinant estrogen receptor erβ, which may be responsible for most of equol’s biological properties. [1]

in vitro

in vitro studies were conducted to measure both the binding affinity of equol for 5alpha-dihydrotestosterone (5alpha-dht) and the effects of equol treatment in human prostate cancer (lncap) cells. it was found that equol bound to 5alpha-dht with maximum and half maxim concentrations of 100 nm and 4.8 nm, respectively. in addition, equol significantly offset the increases in psa levels from lncap cells. [1]

in vivo

an in vivo study was performed to investigate effects of equol on rat prostate weight and circulating levels of sex steroid hormones. 1.0 mg/kg of equol was injected to long-evans rats fed with a low isoflavone diet for 25 days. findings from this study suggested that equol significantly decreased rat prostate weights and down-regulated serum levels of 5alpha-dht. however, this agent did not alter levels of lh, testosterone and estradiol. [1]

References

[1]lund td, blake c, bu l, hamaker an, lephart ed. iequol an isoflavonoid: potential for improved prostate health, in vitro and in vivo evidence. reprod biol endocrin. 2011; 9(4): doi: 10.1186/1477-7827-9-4.
[2]setchell dr and clerici c. equol: pharmacokinetics and biological actions. j nutr. 2010 jul; 140(7): 1363s–8s.

(S)-Equol Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-Equol Suppliers

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View Lastest Price from (S)-Equol manufacturers

Sinoway Industrial co., ltd.
Product
Equol 531-95-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-07-16
Changsha Staherb Natural Ingredients Co., Ltd.
Product
Equol; Soybean extract 531-95-3
Price
US $0.00/KG
Min. Order
1KG
Purity
>99% HPLC
Supply Ability
1000KG
Release date
2022-09-16
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Equol 531-95-3
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-03

531-95-3, (S)-EquolRelated Search:

Dihydromyrcenol Hydroxy silicone oil Triphenylphosphine Tetrahydro-4H-pyran-4-one Centchroman 2-Phenylphenol Aspartame TRIFOLIRHIZIN Rotenone MEDICARPIN morelloflavone Phenylacetone Phenoxodiol pisatin 4',7-DIMETHOXYISOFLAVANONE Dihydrodaidzein Phaseollin (-)-TEPHROSIN

  • (S)-3,4-DYHYDRO-3-(4-HYDROXYPHENYL)-2H-1-BENZOPYRAN-7-OL
  • (S)-4',7-DIHYDROXYISOFLAVANCE
  • R,S-EQUOL
  • (-)-(S)-EQUOL
  • S,R-equol
  • 3-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
  • 4',7-ISOFLAVANDIOL
  • 4',7-DIHYDROXYISOFLAVAN
  • 7,4'-ISOFLAVANDIOL
  • (S)-3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
  • (S)-EQUOL
  • (S)-3-(4-Hydroxy-phenyl)-chroman-7-ol
  • 3-(4-Hydroxy-phenyl)-chroman-7-ol
  • (3S)-3-(4-hydroxyphenyl)chroman-7-ol
  • EQUOL, (+/-)-(SH)
  • EQUOL/()-4'',7-ISOFLAVANDIOL
  • (S)-(-)-4',7-Isoflavandiol
  • (3S)-3-(4-Hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-7-ol
  • (3S)-Equol
  • Equol
  • (3S)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
  • S -Equol [7-hydroxy-3-(49-hydroxyphenyl)-chroMan]
  • 2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-
  • (S)-Equol,99%e.e.
  • (3S)-3,4-Dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol
  • Equol USP/EP/BP
  • 4-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-156-THIOSEMICARBAZIDE
  • (S)-Equol/2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-
  • (S)-7-phenoxy-3-(4-phenoxyphenyl)chromane
  • S-Equol S Equol
  • 531-95-3
  • Food Residue Analysis
  • Analytical Standards
  • Analytical Chromatography Product Catalog
  • Food & Beverage Standards
  • Chromatography
  • Inhibitors
  • Iso-Flavones
  • Chiral Reagents
  • Heterocycles
  • Metabolites & Impurities
  • Metabolites