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2-Propenoic acid, 3,3'-(1,3-phenylene)bis-

Product Name
2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
CAS No.
37710-81-9
Chemical Name
2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
Synonyms
TC AQP1 1;m-Benzenediacrylic acid;TC-AQP1-1, 10 mM in DMSO;m-Phenylenediacrylic acid;TC-AQP-1-1,TCAQP11,TC AQP1 1;3,3'-(1,3-Phenylene)diacrylic acid;3,3'-(1,3-Phenylene)diacrylic acid;2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
CBNumber
CB23207516
Molecular Formula
C12H10O4
Formula Weight
218.21
MOL File
37710-81-9.mol
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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Property

Boiling point:
458.7±33.0 °C(Predicted)
Density 
1.358±0.06 g/cm3(Predicted)
storage temp. 
RT
solubility 
Soluble in DMSO (up to 25 mg/ml).
form 
solid
pka
4.07±0.10(Predicted)
color 
White
Stability:
Stable for 1 year from date of pruchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
5412
Product name
TCAQP11
Purity
≥98%(HPLC)
Packaging
10
Price
$106
Updated
2021/12/16
Tocris
Product number
5412
Product name
TCAQP11
Purity
≥98%(HPLC)
Packaging
50
Price
$445
Updated
2021/12/16
TRC
Product number
T120105
Product name
TCAQP11
Packaging
10mg
Price
$100
Updated
2021/12/16
Usbiological
Product number
256822
Product name
TC AQP1 1
Packaging
10mg
Price
$339
Updated
2021/12/16
Atlantic Research Chemicals
Product number
CA001841
Product name
3-[3-(2-Carboxyeth-1-en-1-yl)phenyl]prop-2-enoicacid
Purity
95%
Packaging
1gm:
Price
$420.61
Updated
2021/12/16
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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Chemical Properties,Usage,Production

Description

CVPA (37710-81-9) is an aquaporin-1 inhibitor (IC50 = 8.1 μM) discovered by molecular docking against the extracellular domain of human aquaporin-1 followed by experimental testing in a Xenopus oocyte swelling assay.1

Uses

TC AQP1 1 is a human aquaoporin-1 (hAQP1) selective inhibitor and is considered to have therapeutic potential towards the potential treatment of glaucoma, brain edema, inflammatory pain and certain types of cancer.

storage

Store at +4°C

References

[1] DANIEL SEELIGER. Discovery of Novel Human Aquaporin-1 Blockers[J]. ACS Chemical Biology, 2012, 8 1: 249-256. DOI:10.1021/cb300153z

2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Propenoic acid, 3,3'-(1,3-phenylene)bis- Suppliers

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37710-81-9, 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-Related Search:

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  • 2-Propenoic acid, 3,3'-(1,3-phenylene)bis-
  • TC AQP1 1
  • TC-AQP-1-1,TCAQP11,TC AQP1 1
  • m-Benzenediacrylic acid
  • m-Phenylenediacrylic acid
  • 3,3'-(1,3-Phenylene)diacrylic acid
  • TC-AQP1-1, 10 mM in DMSO
  • 3,3'-(1,3-Phenylene)diacrylic acid
  • 37710-81-9