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NPC-15437 DIHYDROCHLORIDE

Product Name
NPC-15437 DIHYDROCHLORIDE
CAS No.
136449-85-9
Chemical Name
NPC-15437 DIHYDROCHLORIDE
Synonyms
NPC-15437;NPC154372HCl;Npc1537 dihydrochloride;NPC-15437 DIHYDROCHLORIDE;NPC-15437 hydrate dihydrochloride;2,6-Diamino-N-[(1-tridecanoyl-2-piperidinyl)methyl]hexanamide;Hexanamide, 2,6-diamino-N-[[1-(1-oxotridecyl)-2-piperidinyl]methyl]-, (2S)-;S-2,6-DIAMINO-N-([1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL)HEXANAMIDE DIHYDROCHLORIDE;(2S)-2,6-DIAMINO-N-[[1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE;S-2,6-DIAMINO-N-[[1'-(1'-OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
CBNumber
CB2330262
Molecular Formula
C25H50N4O2
Formula Weight
438.69
MOL File
136449-85-9.mol
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NPC-15437 DIHYDROCHLORIDE Property

storage temp. 
2-8°C
solubility 
H2O: ≥36 mg/mL
form 
solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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NPC-15437 DIHYDROCHLORIDE Chemical Properties,Usage,Production

Biological Activity

Highly selective, competitive and reversible inhibitor of protein kinase C (IC 50 = 19 mM); interacts at the regulatory domain of the enzyme. May modulate P-glycoprotein in tumor cells in vitro via inhibiton of PKC. Centrally active following systemic administration in vivo .

storage

+4°C

NPC-15437 DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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136449-85-9, NPC-15437 DIHYDROCHLORIDERelated Search:


  • S-2,6-DIAMINO-N-([1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL)HEXANAMIDE DIHYDROCHLORIDE
  • S-2,6-DIAMINO-N-[[1'-(1''OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
  • S-2,6-DIAMINO-N-[[1'-(1'-OXOTRIDECYL)-2'-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
  • NPC-15437
  • NPC-15437 DIHYDROCHLORIDE
  • (2S)-2,6-DIAMINO-N-[[1-(1-OXOTRIDECYL)-2-PIPERIDINYL]METHYL]HEXANAMIDE DIHYDROCHLORIDE
  • NPC154372HCl
  • Npc1537 dihydrochloride
  • Hexanamide, 2,6-diamino-N-[[1-(1-oxotridecyl)-2-piperidinyl]methyl]-, (2S)-
  • NPC-15437 hydrate dihydrochloride
  • 2,6-Diamino-N-[(1-tridecanoyl-2-piperidinyl)methyl]hexanamide
  • 136449-85-9
  • C25H50N4O22HCl
  • C25H50N4O2
  • Kinase/Phosphatase Biology
  • Protein Kinase C (PKC)
  • Serine/Threonine Kinase Inhibitors
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Protein Kinase