Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate

Product Name: Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate
CAS No.: 1333382-30-1
Chemical Name: Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate
Synonyms: CX-5011 (sodium salt);Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate
CBNumber: CB23317462
Molecular Formula: C20H11N4NaO2
Formula Weight: 362.33
MOL File: 1333382-30-1.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 20474
Product name: CX-5011 (sodium salt)
Purity: ≥95%
Packaging: 500μg
Price: $25
Updated: 2021/12/16

Cayman Chemical

Product number: 20474
Product name: CX-5011 (sodium salt)
Purity: ≥95%
Packaging: 1mg
Price: $48
Updated: 2021/12/16

Cayman Chemical

Product number: 20474
Product name: CX-5011 (sodium salt)
Purity: ≥95%
Packaging: 5mg
Price: $163
Updated: 2021/12/16

AK Scientific

Product number: SYN5334
Product name: CX-5011
Packaging: 50mg
Price: $1210.95
Updated: 2021/12/16

Matrix Scientific

Product number: 145090
Product name: Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate
Purity: 95%
Packaging: 1g
Price: $18491
Updated: 2021/12/16

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Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate Chemical Properties,Usage,Production

Uses

CX-5011 is a CK2 inhibitor. CX-5011 also induces Rac1 activation. CX-5011 induces apoptosis and induces cancer cell death[1][2].

References

[1] D'Amore C, et al. "Janus" efficacy of CX-5011: CK2 inhibition and methuosis induction by independent mechanisms. Biochim Biophys Acta Mol Cell Res. 2020 Nov;1867(11):118807. DOI:10.1016/j.bbamcr.2020.118807
[2] Salizzato V, et al. Inhibition of protein kinase CK2 by CX-5011 counteracts imatinib-resistance preventing rpS6 phosphorylation in chronic myeloid leukaemia cells: new combined therapeutic strategies. Oncotarget. 2016 Apr 5;7(14):18204-18. DOI:10.18632/oncotarget.7569

Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate Preparation Products And Raw materials

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Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate Suppliers

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1333382-30-1, Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylateRelated Search:

CX-5011 (sodium salt)

Sodium 5-(3-ethynylphenylamino)pyrimido[4,5-c]quinoline-8-carboxylate

1333382-30-1

C20H11N4NaO2