ChemicalBook > CAS DataBase List > 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7

Product Name
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
CAS No.
388622-58-0
Chemical Name
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
Synonyms
7-dehydro Cholesterol-d7;2H7]-7-Dehydrocholesterol;(3Beta)-7-Dehydro Cholesterol-d7;(32)-7-Dehydro Cholesterol-d7 (Major);(3β)-7-Dehydro Cholesterol-d7 (Major);7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;(3β)-7-Dehydro Cholesterol-d7 (See also D229462);7-Dehydrocholesterol (25,26,26,26,27,27,27-D?, 95%);Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;(3β)-7-Dehydro Cholesterol-d7 (Major), CAS 388622-58-0
CBNumber
CB23335585
Molecular Formula
C27H44O
Formula Weight
384.65
MOL File
388622-58-0.mol
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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Property

storage temp. 
-70°C
solubility 
Soluble in methanol(warmed), slightly soluble in chloroform
form 
solid
Stability:
Light Sensitive
InChIKey
UCTLRSWJYQTBFZ-PDTMYDHWNA-N
SMILES
C[C@]12CC[C@]3([H])[C@]4(CC[C@H](O)CC4=CC=C3[C@]1([H])CC[C@]2([H])[C@H](C)CCCC([H])(C([H])([H])[H])C([H])([H])[H])C |&1:1,4,6,9,16,20,22,r|
CAS Number Unlabeled
434-16-2
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Safety

WGK Germany 
3
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
774898
Product name
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
Purity
≥99 atom % D, ≥98% (CP)
Packaging
1mg
Price
$751
Updated
2025/07/31
Sigma-Aldrich
Product number
774898
Product name
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
Purity
≥99 atom % D, ≥98% (CP)
Packaging
5mg
Price
$2869
Updated
2025/07/31
Cayman Chemical
Product number
25969
Product name
7-dehydro Cholesterol-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
500μg
Price
$189
Updated
2024/03/01
Cayman Chemical
Product number
25969
Product name
7-dehydro Cholesterol-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
1mg
Price
$340
Updated
2024/03/01
TRC
Product number
D229457
Product name
(3β)-7-DehydroCholesterol-d7
Packaging
0.5mg
Price
$180
Updated
2021/12/16
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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemical Properties,Usage,Production

Uses

7-dehydrocholesterol-d7 has been used:

  • as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis
  • in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis
  • to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis

General Description

7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol.

Biochem/physiol Actions

7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS).

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Preparation Products And Raw materials

Raw materials

Preparation Products

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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Suppliers

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388622-58-0, 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7Related Search:


  • (32)-7-Dehydro Cholesterol-d7 (Major)
  • 7-dehydro Cholesterol-d7
  • 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
  • Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-
  • (3β)-7-Dehydro Cholesterol-d7 (Major)
  • (3β)-7-Dehydro Cholesterol-d7 (See also D229462)
  • 2H7]-7-Dehydrocholesterol
  • Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7)
  • (3Beta)-7-Dehydro Cholesterol-d7
  • 7-Dehydrocholesterol-25,26,26,26,27,27,27-d<sub>7</sub>
  • (3β)-7-Dehydro Cholesterol-d7 (Major), CAS 388622-58-0
  • 7-Dehydrocholesterol (25,26,26,26,27,27,27-D?, 95%)
  • 388622-58-0