ChemicalBook > CAS DataBase List > 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
- Product Name
- 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
- CAS No.
- 388622-58-0
- Chemical Name
- 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
- Synonyms
- 7-dehydro Cholesterol-d7;2H7]-7-Dehydrocholesterol;(32)-7-Dehydro Cholesterol-d7 (Major);(3β)-7-Dehydro Cholesterol-d7 (Major);7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;(3β)-7-Dehydro Cholesterol-d7 (See also D229462);Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7)
- CBNumber
- CB23335585
- Molecular Formula
- C27H44O
- Formula Weight
- 384.65
- MOL File
- 388622-58-0.mol
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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Property
- storage temp.
- -70°C
- solubility
- Soluble in methanol(warmed), slightly soluble in chloroform
- form
- solid
- Stability:
- Light Sensitive
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 774898
- Product name
- 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
- Purity
- ≥99 atom % D, ≥98% (CP)
- Packaging
- 1mg
- Price
- $719
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 774898
- Product name
- 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
- Purity
- ≥99 atom % D, ≥98% (CP)
- Packaging
- 5mg
- Price
- $2890
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25969
- Product name
- 7-dehydro Cholesterol-d7
- Purity
- ≥99% deuterated forms (d1-d7)
- Packaging
- 500μg
- Price
- $189
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 25969
- Product name
- 7-dehydro Cholesterol-d7
- Purity
- ≥99% deuterated forms (d1-d7)
- Packaging
- 1mg
- Price
- $340
- Updated
- 2024/03/01
TRC
- Product number
- D229457
- Product name
- (3β)-7-DehydroCholesterol-d7
- Packaging
- 0.5mg
- Price
- $180
- Updated
- 2021/12/16
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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemical Properties,Usage,Production
Uses
7-dehydrocholesterol-d7 has been used:
- as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis
- in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis
- to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis
General Description
7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol.
Biochem/physiol Actions
7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS).
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Preparation Products And Raw materials
Raw materials
Preparation Products
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