PKM2 inhibitor

Product Name: PKM2 inhibitor
CAS No.: 94164-88-2
Chemical Name: PKM2 inhibitor
Synonyms: PKM2-IN-1;compound 3k;PKM2 inhibitor;PKM2 inhibitor 1;PKM2-IN-1;COMPOUND 3K;PKM2-IN-1, 10 mM in DMSO;PKM2 inhibitor(compound 3k);Pyruvate Kinase,inhibit,PKM2 IN 1,Inhibitor,PKM2IN1,PKM-2-IN-1;(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl piperidine-1-carbodithioate;piperidine-1-carbodithioic acid 3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-ylmethyl ester
CBNumber: CB23350586
Molecular Formula: C18H19NO2S2
Formula Weight: 345.48
MOL File: 94164-88-2.mol

More

Less

PKM2 inhibitor Property

Boiling point:: 496.5±55.0 °C(Predicted)
Density: 1.302±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
solubility: DMF: 1 mg/ml; DMSO: insol; Ethanol: insol; PBS (pH 7.2): insol
form: A solid
pka: 0.81±0.20(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P571505
Product name: PKM2-IN-1
Packaging: 5mg
Price: $215
Updated: 2021/12/16

ChemScene

Product number: CS-8094
Product name: PKM2-IN-1
Purity: 96.55%
Packaging: 5mg
Price: $96
Updated: 2021/12/16

ChemScene

Product number: CS-8094
Product name: PKM2-IN-1
Purity: 96.55%
Packaging: 10mg
Price: $144
Updated: 2021/12/16

AK Scientific

Product number: 2010EL
Product name: PKM2inhibitor
Packaging: 250mg
Price: $205
Updated: 2021/12/16

ChemScene

Product number: CS-8094
Product name: PKM2-IN-1
Purity: 96.55%
Packaging: 50mg
Price: $504
Updated: 2021/12/16

More

Less

PKM2 inhibitor Chemical Properties,Usage,Production

Uses

PKM2-IN-1, is a pyruvate kinase M2 (PKM2) inhibitor with an IC50 of 2.95 μM.

Biological Activity

Pyruvate kinase M2 (PKM2) inhibitor superior to shikonin.
Compound 3k (C3k) is a pyruvate kinase M2 (PKM2) inhibitor with 3-fold higher potency than shikonin (IC50 = 2.95 and 8.82 μM, respectively, by in vitro PKM2 LDH coupled assay). C3k exhibits potent cancer cell-selective antiproliferative activity in high PKM2-expressing cancer cultures (HCT116/HeLA/H1299 IC50 = 0.18/0.29/1.56 μM with C3k, 1.84/2.45/1.88 μM with shikonin) with much less cytotoxicity toward normal BEAS-2B human bronchial epithelial cells (IC50 = 18.46 μM; IC50 = 5.36 μM with shikonin).

PKM2 inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PKM2 inhibitor Suppliers

China 52 India 1 United States 6 Global 59

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4727
Advantage: 58

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1874
Advantage: 55

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6787
Advantage: 55

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4588
Advantage: 55

Shanghaizehan biopharma technology co., Ltd.

Tel: 021-61350663 13052117465
Fax: 021-61350662
Email: sales@zehanbiopharma.com
Country: China
ProdList: 1004
Advantage: 55

Shanghai Beckham Medical Technology Co., Ltd

Tel: 021-13816613772 13816613772
Fax: QQ: 12922499
Email: huahero21@sina.com
Country: China
ProdList: 765
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29764
Advantage: 68

Medi-tech Bioscientific Co., Ltd.

Tel: 0519-83246372 13585352506
Fax: 0519-83246372
Country: China
ProdList: 1844
Advantage: 58

94164-88-2, PKM2 inhibitorRelated Search:

PKM2 inhibitor

PKM2-IN-1

compound 3k

PKM2 inhibitor(compound 3k)

PKM2-IN-1;COMPOUND 3K

piperidine-1-carbodithioic acid 3-methyl-1,4-dioxo-1,4-dihydronaphthalen-2-ylmethyl ester

PKM2 inhibitor 1

1-Piperidinecarbodithioic acid, (1,4-dihydro-3-methyl-1,4-dioxo-2-naphthalenyl)methyl ester

Pyruvate Kinase,inhibit,PKM2 IN 1,Inhibitor,PKM2IN1,PKM-2-IN-1

(3-Methyl-1,4-dioxo-1,4-dihydronaphthalen-2-yl)methyl piperidine-1-carbodithioate

PKM2-IN-1, 10 mM in DMSO

94164-88-2