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Bis-(N,N'-carboxyl-PEG4)-Cy5

Product Name
Bis-(N,N'-carboxyl-PEG4)-Cy5
CAS No.
2107273-44-7
Chemical Name
Bis-(N,N'-carboxyl-PEG4)-Cy5
Synonyms
Bis-(N,N'-carboxyl-PEG4)-Cy5
CBNumber
CB23363883
Molecular Formula
C47H67ClN2O12
Formula Weight
887.51
MOL File
2107273-44-7.mol
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Bis-(N,N'-carboxyl-PEG4)-Cy5 Property

solubility 
Soluble in Water, DMSO, DMF, DCM
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23033
Product name
Bis-(N,N'-carboxyl-PEG4)-Cy5
Purity
98%
Packaging
1mg
Price
$220
Updated
2021/12/16
BroadPharm
Product number
BP-23033
Product name
Bis-(N,N'-carboxyl-PEG4)-Cy5
Purity
98%
Packaging
2mg
Price
$350
Updated
2021/12/16
BroadPharm
Product number
BP-23033
Product name
Bis-(N,N'-carboxyl-PEG4)-Cy5
Purity
98%
Packaging
5mg
Price
$650
Updated
2021/12/16
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Bis-(N,N'-carboxyl-PEG4)-Cy5 Chemical Properties,Usage,Production

Description

Bis-(N,N'-carboxyl-PEG4)-Cy5 is a PEG linker containing a cyanine dye with excitation/emmission maximum 649/667 nm and a free terminal carboxyl acid. Terminal carboxylic acid can react with primary amine groups in the presence of of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydophilic PEG spacer increases solubility in aqueous media.

Uses

Bis-(N,N'-carboxyl-PEG4)-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bis-(N,N'-carboxyl-PEG4)-Cy5 Preparation Products And Raw materials

Raw materials

Preparation Products

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Bis-(N,N'-carboxyl-PEG4)-Cy5 Suppliers

China 11 United States 2 Global 13
Jinan elephant international trading co., LTD
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Zhengzhou Acme Chemical Co., Ltd.
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TargetMol Chemicals Inc.
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Beijing Jin Ming Biotechnology Co., Ltd.
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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Jilin Chinese Academy of Sciences-yanshen Technology
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Chongqing Botao Biotechnology Co., LTD
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TargetMol Chemicals Inc.
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Chongqing jooe co., ltd
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