ChemicalBook > CAS DataBase List > GEN6776

GEN6776

Product Name: GEN6776
CAS No.: 2009273-71-4
Chemical Name: GEN6776
Synonyms: GEN6776;CS-2823;GNE-6776;GEN-6776 ，S6933;GEN6776 GNE-6776;GNE-6776, 10 mM in DMSO;GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776;6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide;[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-;5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
CBNumber: CB23367720
Molecular Formula: C20H20N4O2
Formula Weight: 348.4
MOL File: 2009273-71-4.mol

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GEN6776 Property

Boiling point:: 609.7±55.0 °C(Predicted)
Density: 1.242±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 310 mg/mL (889.78 mM)
form: Solid
pka: 8.14±0.15(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: BG166813
Product name: GNE 6776
Packaging: 10mg
Price: $185
Updated: 2021/12/16

ChemScene

Product number: CS-0031103
Product name: GNE-6776
Purity: 98.29%
Packaging: 5mg
Price: $220
Updated: 2021/12/16

AK Scientific

Product number: 3226EH
Product name: 5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
Packaging: 10mg
Price: $299
Updated: 2021/12/16

ChemScene

Product number: CS-0031103
Product name: GNE-6776
Purity: 98.29%
Packaging: 10mg
Price: $350
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BG166813
Product name: GNE 6776
Packaging: 50mg
Price: $647.5
Updated: 2021/12/16

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GEN6776 Chemical Properties,Usage,Production

Uses

GNE6776, is a selective USP7 inhibitor.

in vivo

GNE-6776 (100 or 200 mg/kg; oral gavage on a once or twice daily schedule; for 10 days) inhibits EOL-1 xenograft growth in mice^[1].

Animal Model:	Immunodeficient C.B-17 SCID mice (aged 12-16 weeks) with EOL1 AML xenograft^[1]
Dosage:	100 or 200?mg/kg
Administration:	Oral gavage on a once or twice daily schedule; for 10 days
Result:	Significant EOL-1 xenograft growth inhibition.

GEN6776 Preparation Products And Raw materials

Raw materials

Preparation Products

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2009273-71-4, GEN6776Related Search:

GEN6776

GNE-6776

CS-2823

GEN6776 GNE-6776

6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide

[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-

5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide

GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776

GNE-6776, 10 mM in DMSO

GEN-6776 ，S6933

2009273-71-4

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