ChemicalBook > CAS DataBase List > (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- Product Name
- (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- CAS No.
- 1417997-93-3
- Chemical Name
- (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide
- Synonyms
- 22d;HDAC8-IN-1;CS-2693;MDK-7933;INVIVO-7933;HDAC8-IN-22d;HDAC8-IN-1(22d);HDAC8 inhibitor 1;HDAC8 inhibitor 22d;HDAC8-IN-1 ,MDK7933
- CBNumber
- CB23373154
- Molecular Formula
- C22H19NO3
- Formula Weight
- 345.39
- MOL File
- 1417997-93-3.mol
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(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Property
- Density
- 1?+-.0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: soluble
- form
- A solid
- pka
- 8.76±0.23(Predicted)
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28832
- Product name
- HDAC8-IN-1
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28832
- Product name
- HDAC8-IN-1
- Packaging
- 25mg
- Price
- $692
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28832
- Product name
- HDAC8-IN-1
- Packaging
- 5mg
- Price
- $172
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28832
- Product name
- HDAC8-IN-1
- Packaging
- 10mg
- Price
- $321
- Updated
- 2024/03/01
TRC
- Product number
- H805220
- Product name
- (2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide
- Packaging
- 5mg
- Price
- $275
- Updated
- 2021/12/16
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(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Chemical Properties,Usage,Production
Description
HDAC8-IN-1 is an inhibitor of histone deacetylase 8 (HDAC8; IC50 = 27.2 nM). It is selective for HDAC8 over HDAC1-3, -4, -6, -10, and -11 (IC50s = ≥3,000 nM for all). HDAC8-IN-1 is cytotoxic to A549, H1299, and CL1-5 lung cancer cells (IC50s = 7.9, 7.2, and 7 μM, respectively).
Uses
(2E)-N-Hydroxy-3-(5-methoxy[1,1'':4'',1''''-terphenyl]-2-yl)-2-propenamide, is a HDAC8 inhibitor with an IC50 of 27.2 nM.
(E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamide Preparation Products And Raw materials
Raw materials
Preparation Products
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1417997-93-3, (E)-N-hydroxy-4-methoxy-2-(biphenyl-4-yl)cinnamamideRelated Search:
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