Aminooxy-PEG3-methyl ester
- Product Name
- Aminooxy-PEG3-methyl ester
- CAS No.
- 2086689-03-2
- Chemical Name
- Aminooxy-PEG3-methyl ester
- Synonyms
- Aminooxy-PEG3-methyl ester;Propanoic acid, 3-[2-[2-[2-(aminooxy)ethoxy]ethoxy]ethoxy]-, methyl ester
- CBNumber
- CB23373558
- Molecular Formula
- C10H21NO6
- Formula Weight
- 251.28
- MOL File
- 2086689-03-2.mol
Aminooxy-PEG3-methyl ester Property
- Boiling point:
- 361.4±32.0 °C(Predicted)
- Density
- 1?+-.0.06 g/cm3(Predicted)
- pka
- 4.21±0.70(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-23527
- Product name
- Aminooxy-PEG3-methylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- BP-23527
- Product name
- Aminooxy-PEG3-methylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $560
- Updated
- 2021/12/16
- Product number
- BP-23527
- Product name
- Aminooxy-PEG3-methylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $860
- Updated
- 2021/12/16
Aminooxy-PEG3-methyl ester Chemical Properties,Usage,Production
Description
Aminooxy-PEG3-CH2CO2tBu consist of an aminooxy group and a t-butyl ester group. Aminooxy(ONH2) group can be used in bioconjugation. It is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl protected carboxyl group can be hydrolyzed to form a free acid. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.
Uses
Aminooxy-PEG3-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Aminooxy-PEG3-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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