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N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)

Product Name
N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)
CAS No.
2112730-79-5
Chemical Name
N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)
Synonyms
N-(Biotin-PEG4)-N-bis(PEG4-Boc);N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester);4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[20-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-16-oxo-3,6,9,12-tetraoxa-15-azaeicos-1-yl]-, 1,31-bis(1,1-dimethylethyl) ester
CBNumber
CB23373705
Molecular Formula
C50H94N4O18S
Formula Weight
1071.36
MOL File
2112730-79-5.mol
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N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Property

Boiling point:
996.2±65.0 °C(Predicted)
Density 
1.121±0.06 g/cm3(Predicted)
pka
13.90±0.40(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23528
Product name
N-(Biotin-PEG4)-N-bis(PEG4-t-butylester)
Purity
96%
Packaging
100mg
Price
$330
Updated
2021/12/16
BroadPharm
Product number
BP-23528
Product name
N-(Biotin-PEG4)-N-bis(PEG4-t-butylester)
Purity
96%
Packaging
250mg
Price
$650
Updated
2021/12/16
BroadPharm
Product number
BP-23528
Product name
N-(Biotin-PEG4)-N-bis(PEG4-t-butylester)
Purity
96%
Packaging
500mg
Price
$980
Updated
2021/12/16
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N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Chemical Properties,Usage,Production

Biological Activity

N-(Biotin-PEG4)-N-bis(PEG4-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester) Suppliers

China 2 United States 2 Global 4
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
ProdList
9966
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29774
Advantage
58

2112730-79-5, N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)Related Search:


  • N-(Biotin-PEG4)-N-bis(PEG4-t-butyl ester)
  • N-(Biotin-PEG4)-N-bis(PEG4-Boc)
  • 4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[20-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-16-oxo-3,6,9,12-tetraoxa-15-azaeicos-1-yl]-, 1,31-bis(1,1-dimethylethyl) ester
  • 2112730-79-5
  • C50H94N4O18S