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JQEZ5

Product Name: JQEZ5
CAS No.: 1913252-04-6
Chemical Name: JQEZ5
Synonyms: JQZ5;JQEZ5;CS-2764;JQ-EZ-05;JQ-EZ-05 (JQEZ5);JQEZ5;JQE-Z5;JQE Z5;JQEZ5, 10 mM in DMSO;S-adenosyl,EZH2,JQEZ5,antitumor,methionine,JQEZ 5,H3K27me3,PRC2,inhibit,Inhibitor,JQEZ-5,Histone Methyltransferase;1-Isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide;N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide
CBNumber: CB23386491
Molecular Formula: C30H38N8O2
Formula Weight: 542.68
MOL File: 1913252-04-6.mol

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JQEZ5 Property

storage temp.: Store at -20°C
solubility: DMSO:17.93(Max Conc. mg/mL);33.03(Max Conc. mM)
form: A crystalline solid
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 27457
Product name: JQEZ5
Packaging: 5mg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 27457
Product name: JQEZ5
Packaging: 50mg
Price: $812
Updated: 2024/03/01

Cayman Chemical

Product number: 27457
Product name: JQEZ5
Packaging: 10mg
Price: $195
Updated: 2024/03/01

Cayman Chemical

Product number: 27457
Product name: JQEZ5
Packaging: 25mg
Price: $459
Updated: 2024/03/01

Tocris

Product number: 6153
Product name: JQEZ5
Purity: ≥98%(HPLC)
Packaging: 10
Price: $169
Updated: 2021/12/16

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JQEZ5 Chemical Properties,Usage,Production

Uses

JQEZ5, is a novel and potent EZH2 inhibitor.

in vivo

JQEZ5 (75 mg/kg; intraperitoneal injection; daily; for 3 weeks) treatment exhibits rapid and pronounced tumor regression over the three week treatment course. And H3K27me3 levels are largely reduced with treatment further confirming the on-target effect of JQEZ5 in mice^[1].

IC 50

EZH2

storage

Store at -20°C

JQEZ5 Preparation Products And Raw materials

Raw materials

Preparation Products

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JQEZ5 Suppliers

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1913252-04-6, JQEZ5Related Search:

JQEZ5

JQ-EZ-05

JQ-EZ-05 (JQEZ5)

JQEZ5;JQE-Z5;JQE Z5

CS-2764

N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxamide

JQZ5

1H-Pyrazolo[3,4-b]pyridine-4-carboxamide, N-[(1,2-dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[6-(4-methyl-1-piperazinyl)-3-pyridinyl]-

S-adenosyl,EZH2,JQEZ5,antitumor,methionine,JQEZ 5,H3K27me3,PRC2,inhibit,Inhibitor,JQEZ-5,Histone Methyltransferase

1-Isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide

JQEZ5, 10 mM in DMSO

JQEZ5,1-isopropyl-N-((6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl)-6-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxamide

1913252-04-6

C30H38N8O2