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ChemicalBook > CAS DataBase List > (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE

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Product Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
CAS No.
221012-82-4
Chemical Name
(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
Synonyms
(S)-P-PHOS;(R)-P-PHOS;CTH-(R)-P-PHOS;CTH-(S)-P-PHOS;(R)-(+)-2,2'',6,6''-Tetramethoxy-4,4''-bis(diphenylphosphino)-3;(R)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine;(3R)-4,4'-Bis(diphenylphosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine;(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3-BIPYRIDINE;(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE;(R)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
CBNumber
CB2346621
Molecular Formula
C38H34N2O4P2
Formula Weight
644.64
MOL File
221012-82-4.mol
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE Property

Melting point:
261-265°C
Boiling point:
686.1±55.0 °C(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-2.99±0.20(Predicted)
form 
Powder
color 
white to pale yellow
optical activity
[α]20/D +98°, c = 1 in chloroform
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
675806
Product name
(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine
Purity
97%
Packaging
100mg
Price
$101
Updated
2024/03/01
Sigma-Aldrich
Product number
675806
Product name
(R)-(+)-2,2′,6,6′-Tetramethoxy-4,4′-bis(diphenylphosphino)-3,3′-bipyridine
Purity
97%
Packaging
500mg
Price
$412
Updated
2023/06/20
Strem Chemicals
Product number
15-5200
Product name
(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine, min. 97% CTH-(R)-P-Phos
Packaging
100mg
Price
$78
Updated
2024/03/01
Strem Chemicals
Product number
15-5200
Product name
(R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine, min. 97% CTH-(R)-P-Phos
Packaging
500mg
Price
$316
Updated
2024/03/01
ChemScene
Product number
CS-0092889
Product name
(R)-P-Phos
Purity
>97.0%
Packaging
100mg
Price
$123
Updated
2021/12/16
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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE Chemical Properties,Usage,Production

Reaction

  1. New class of highly effective chiral dipyridylphosphine ligands used in the asymmetric hydrogenation of 2-arylacrylic acids, β-ketoesters, aryl ketones, and α-dehydroamino acids.
  2. Ligand used in the Pd-catalyzed asymmetric bis-alkoxycarbonylation of styrene.

Chemical Properties

White solid

Uses

Ligand employed in the asymmetic hydrogenation of ?-keto esters, 2-arylacrylates, aryl ketones , and other substrates.

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE Suppliers

China 28 Germany 2 India 1 Norway 1 Switzerland 1 The Netherlands 1 United States 5 Global 39
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221012-82-4, (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINERelated Search:

(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE (R)-XYL-P-PHOS RUTHENIUMCL2 (R,R)-DPEN DICHLORO[(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE][(1R,2R)-(+)-1,2-DIPHENYLETHYLENEDIAMINE]RUTHENIUM (II), MIN. 95 (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE (R)-P-PHOS RUTHENIUM (ACAC)2 (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE DICHLORO[(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE][(1S,2S)-(-)-1,2-DIPHENYLETHYLENEDIAMINE]RUTHENIUM (II), MIN. 95 (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE(1,5-CYCLOOCTADIENE)RHODIUM(I) TETRAFLUOROBORATE DICHLORO[(S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE][(1S,2S)-(-)-1,2-DIPHENYLETHYLENEDIAMINE]RUTHENIUM (II), MIN. 95 DICHLORO[(R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DI(3,5-XYLYL)PHOSPHINO)-3,3'-BIPYRIDINE][(1R,2R)-(+)-1,2-DIPHENYLETHYLENEDIAMINE]RUTHENIUM (II)

  • CTH-(S)-P-PHOS
  • CTH-(R)-P-PHOS
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
  • (S)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3-BIPYRIDINE
  • (R)-P-PHOS
  • (S)-P-PHOS
  • (R)-(-)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE
  • (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine,min.95%CTH-(R)-P-PHOS
  • (r)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine *cth-(r)-p-phos*
  • (R)-(-)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine Application:Asymmetric hydrogenation Store N2Ar
  • (3R)-4,4'-Bis(diphenylphosphino)-2,2',6,6'-tetramethoxy-3,3'-bipyridine
  • (R)-(+)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine 97%
  • (R)-(+)-2,2',6,6'-TETRAMETHOXY-4,4'-BIS(DIPHENYLPHOSPHINO)-3,3'-BIPYRIDINE,MIN.97%CTH-(R)-P-PHOS
  • 3,3'-Bipyridine, 4,4'-bis(diphenylphosphino)-2,2',6,6'-tetramethoxy-, (3R)-
  • (R)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine[(R)-P-Phos]
  • (R)-(+)-2,2'',6,6''-Tetramethoxy-4,4''-bis(diphenylphosphino)-3
  • (R)-2,2',6,6'-Tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine
  • 221012-82-4
  • C38H34N2O4P2
  • Hydrogenation
  • Chiral Catalysts, Ligands, and Reagents
  • Asymmetric Synthesis