19-HYDROXYTESTOSTERONE-19-CME Property

Melting point:

192-194 °C

storage temp. 

2-8°C

solubility 

Acetonitrile (Slightly), Methanol (Slightly)

form 

Solid

color 

White to Off-White

Safety

Hazard Codes 

Xn

Risk Statements 

61-40-20/21/22-63

Safety Statements 

53-22-36/37/39-36/37

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

H351Suspected of causing cancer

H361Suspected of damaging fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P281Use personal protective equipment as required.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P405Store locked up.

P501Dispose of contents/container to..…

19-HYDROXYTESTOSTERONE-19-CME Chemical Properties,Usage,Production

Uses

19-Hydroxytestosterone-19-CME is a derivative of 19-Hydroxyandrostendione (H801500), a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.

Uses

16α-Hydroxytestosterone is an metabolite of Testosterone (T155000), the major circulating androgen. Testosterone was found to be metabolized by cytochrome P-450 to 16α-Hydroxytestosterone in rat liver .

Definition

ChEBI: 16alpha-hydroxytestosterone is a C19-steroid that is testosterone in which the hydrogen at the 16alpha position has been replaced by a hydroxy group. It has a role as an androgen. It is a 3-oxo-Delta(4) steroid, a 16alpha-hydroxy steroid, a 17beta-hydroxy steroid, a C19-steroid, an androstanoid, a diol and a secondary alcohol. It is functionally related to a testosterone.