5-Bromo-4-cyclopropyl-6-methoxypyrimidine
- Product Name
- 5-Bromo-4-cyclopropyl-6-methoxypyrimidine
- CAS No.
- 1649454-57-8
- Chemical Name
- 5-Bromo-4-cyclopropyl-6-methoxypyrimidine
- Synonyms
- 5-bromo-4-cyclopropyl-6-methoxypyrimidine;Pyrimidine, 5-bromo-4-cyclopropyl-6-methoxy-;WX192148,5-bromo-4-cyclopropyl-6-methoxypyrimidine;5-bromo-4-cyclopropyl-6-methoxypyrimidine(WX192148);5-bromo-4-cyclopropyl-6-methoxypyrimidine - [AC77951]
- CBNumber
- CB23617757
- Molecular Formula
- C8H9BrN2O
- Formula Weight
- 229.07
- MOL File
- 1649454-57-8.mol
5-Bromo-4-cyclopropyl-6-methoxypyrimidine Property
- Boiling point:
- 289.3±40.0 °C(Predicted)
- Density
- 1.590±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 2.13±0.28(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C8H9BrN2O/c1-12-8-6(9)7(5-2-3-5)10-4-11-8/h4-5H,2-3H2,1H3
- InChIKey
- FHEYKQYHQQAZBJ-UHFFFAOYSA-N
- SMILES
- C1=NC(OC)=C(Br)C(C2CC2)=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
5-Bromo-4-cyclopropyl-6-methoxypyrimidine Chemical Properties,Usage,Production
Synthesis
To a solution of 4-cyclopropyl-6-methoxypyrimidine (1.6 g, 10.7 mmol) in EtOH (10 mL) was added Bn (1.87 g, 11.7 mmol) at -20 °C. The resulting mixture was slowly warmed to room temperature and stirred at the same temperature for 16 h. Solvent was removed under reduced pressure and the residue dissolved in EtOAc and washed with saturated Na2C03, water and brine. The organic layer was dried over Na2SO4 and concentrated to give 5-bromo-4-cyclopropyl-6-methoxypyrimidine (2.3 g).
5-Bromo-4-cyclopropyl-6-methoxypyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-4-cyclopropyl-6-methoxypyrimidine Suppliers
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