2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID
- Product Name
- 2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID
- CAS No.
- 298186-80-8
- Chemical Name
- 2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID
- Synonyms
- CAY10444;BML-241;CAY10444 Exclusive;CAY10444, 10 mM in DMSO;FNBSOIBCKUUVJJ-LSLKUGRBSA-N;2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID;2-Undecylthiazolidine-4(R)-carboxylic acid;(4R)-2-Undecyl-4-thiazolidinecarboxylic acid;4-Thiazolidinecarboxylic acid, 2-undecyl-, (4R)-;(4R)-2-Undecyl-4-thiazolidinecarboxylic acid >=98% (HPLC)
- CBNumber
- CB2367523
- Molecular Formula
- C15H29NO2S
- Formula Weight
- 287.46
- MOL File
- 298186-80-8.mol
2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID Property
- Boiling point:
- 439.2±40.0 °C(Predicted)
- Density
- 1.017±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: >5mg/mL
- pka
- 2.09±0.40(Predicted)
- form
- powder
- color
- white to off-white
Safety
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
N-Bromosuccinimide Price
- Product number
- 10005033
- Product name
- CAY10444
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $54
- Updated
- 2024/03/01
- Product number
- 10005033
- Product name
- CAY10444
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $98
- Updated
- 2024/03/01
- Product number
- 10005033
- Product name
- CAY10444
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $231
- Updated
- 2024/03/01
- Product number
- 10005033
- Product name
- CAY10444
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $410
- Updated
- 2024/03/01
- Product number
- SYN5514
- Product name
- CAY10444
- Packaging
- 50mg
- Price
- $336
- Updated
- 2021/12/16
2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID Chemical Properties,Usage,Production
Uses
CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors[1].
Definition
ChEBI: 4-thiazolidinecarboxylic acid, 2-undecyl-, (4r)- is a L-alpha-amino acid.
Biological Activity
CAY10444 is a selective sphingosine-1-phosphate (S1P) receptor 3 (S1P3; EDG3) antagonist th at inhibits 1 μM S1P-induced calcium mobilization in HeLa transfectants th at express S1P3 over those expressing S1P1/CD363/EDG1 (37.6% vs 6.92% inhibition by 10 μM CAY10444).
IC 50
S1PR3
References
[1] Salvatore Salomone, et al. Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol. 2011 Feb 22;2:9. DOI:10.3389/fphar.2011.00009
2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID manufacturers
- Product
- 2-UNDECYL-THIAZOLIDINE-4-CARBOXYLIC ACID 298186-80-8
- Price
- US $110.00-1100.00/KG
- Min. Order
- 1KG
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-09-26