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(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid

Product Name
(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
CAS No.
1798304-51-4
Chemical Name
(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
Synonyms
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid;CID 123348063;4-Cyclopropyl-6-methoxypyrimidine-5-boronic Acid;B-(4-Cyclopropyl-6-methoxy-pyrimidin-5-yl)boronic acid;Boronic acid, B-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-;(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid(WX192149);(4-cyclopropyl-6-methoxy-pyrimidin-5-yl)boronic acid - [C83800]
CBNumber
CB23940002
Molecular Formula
C8H11BN2O3
Formula Weight
194
MOL File
1798304-51-4.mol
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(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Property

Boiling point:
402.1±55.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
2-8°C, sealed storage, away from moisture
pka
2.49±0.58(Predicted)
Appearance
White to off-white Solid
InChI
InChI=1S/C8H11BN2O3/c1-14-8-6(9(12)13)7(5-2-3-5)10-4-11-8/h4-5,12-13H,2-3H2,1H3
InChIKey
BYXHEUWWJYYRNH-UHFFFAOYSA-N
SMILES
B(C1=C(OC)N=CN=C1C1CC1)(O)O
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Aaron Chemicals
Product number
AR01DJ9W
Product name
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronicacid
Purity
95%
Packaging
100mg
Price
$292
Updated
2021/12/16
1Pluschem
Product number
1P01DJ1K
Product name
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid(WX192149)
Purity
95%
Packaging
100mg
Price
$340
Updated
2021/12/16
Aaron Chemicals
Product number
AR01DJ9W
Product name
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronicacid
Purity
95%
Packaging
250mg
Price
$505
Updated
2021/12/16
1Pluschem
Product number
1P01DJ1K
Product name
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid(WX192149)
Purity
95%
Packaging
250mg
Price
$536
Updated
2021/12/16
1Pluschem
Product number
1P01DJ1K
Product name
(4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid(WX192149)
Purity
95%
Packaging
1g
Price
$969
Updated
2021/12/16
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(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Chemical Properties,Usage,Production

Synthesis

To a stirred solution of 5-bromo-4-cyclopropyl-6-methoxy-pyrimidine in toluene and tetrahydrofuran was added triisopropyl borate at room temperature under nitrogen atmosphere. The mixture was cooled down to -70 °C. To the above mixture was slowly added n-butyl lithium dropwise at -70 °C. The resulting mixture was stirred for additional 15 min at -70 °C. The reaction was quenched with 1N HCl at -70 °C. The mixture was purified by RP-Flash, the collected fractions were combined and concentrated under reduced pressure to afford (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid (3.5 g, 18.04 mmol, 94% yield) as a white solid.

(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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(4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid Suppliers

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1798304-51-4, (4-Cyclopropyl-6-methoxypyrimidin-5-yl)boronic acidRelated Search:


  • (4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid(WX192149)
  • (4-cyclopropyl-6-methoxypyrimidin-5-yl)boronic acid
  • Boronic acid, B-(4-cyclopropyl-6-methoxy-5-pyrimidinyl)-
  • B-(4-Cyclopropyl-6-methoxy-pyrimidin-5-yl)boronic acid
  • 4-Cyclopropyl-6-methoxypyrimidine-5-boronic Acid
  • (4-cyclopropyl-6-methoxy-pyrimidin-5-yl)boronic acid - [C83800]
  • CID 123348063
  • 1798304-51-4