Cilofexor

ChemicalBook > CAS DataBase List > Cilofexor

Product Name: Cilofexor
CAS No.: 1418274-28-8
Chemical Name: Cilofexor
Synonyms: CS-2761;Cilofexor;Cilofexor （GS-9674);GS-9674;GS9674;CILOFEXOR;2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid;GS9674,Inhibitor,inhibit,NR1H4,FXR,Cilofexor,PSC,GS 9674,oral,NASH,GS-9674,antifibrotic,nonsteroidal,anti-inflammatory,Autophagy,safety;4-Pyridinecarboxylic acid, 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-;2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid
CBNumber: CB23956597
Molecular Formula: C28H22Cl3N3O5
Formula Weight: 586.85
MOL File: 1418274-28-8.mol

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Cilofexor Property

Boiling point:: 855.5±65.0 °C(Predicted)
Density: 1.538±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:32.5(Max Conc. mg/mL);55.38(Max Conc. mM)
form: A crystalline solid
pka: 2.10±0.10(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25747
Product name: Cilofexor
Purity: ≥98%
Packaging: 1mg
Price: $39
Updated: 2024/03/01

Cayman Chemical

Product number: 25747
Product name: Cilofexor
Purity: ≥98%
Packaging: 5mg
Price: $202
Updated: 2024/03/01

Cayman Chemical

Product number: 25747
Product name: Cilofexor
Purity: ≥98%
Packaging: 10mg
Price: $363
Updated: 2024/03/01

Cayman Chemical

Product number: 25747
Product name: Cilofexor
Purity: ≥98%
Packaging: 25mg
Price: $745
Updated: 2024/03/01

ChemScene

Product number: CS-0039260
Product name: Cilofexor
Purity: 99.82%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

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Cilofexor Chemical Properties,Usage,Production

Description

Cilofexor inhibits binding of a synthetic peptide, comprising residues 676-700 of the steroid receptor coactivator 1 (SRC-1), to the farnesoid X receptor (FXR; EC₅₀ = <25 nM in a FRET activity assay). It has FXR agonist activity in a mammalian one hybrid (M1H) assay (EC₅₀ = ≥100 nM).

Cilofexor Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cilofexor manufacturers

Career Henan Chemical Co

Product: Cilofexor 1418274-28-8
Price: US $9.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

1418274-28-8, CilofexorRelated Search:

Cilofexor

Cilofexor （GS-9674)

2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid

GS-9674;GS9674;CILOFEXOR

CS-2761

2-[3-(2-chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)-3-hydroxyazetidin-1-yl]pyridine-4-carboxylic acid

4-Pyridinecarboxylic acid, 2-[3-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]-3-hydroxy-1-azetidinyl]-

GS9674,Inhibitor,inhibit,NR1H4,FXR,Cilofexor,PSC,GS 9674,oral,NASH,GS-9674,antifibrotic,nonsteroidal,anti-inflammatory,Autophagy,safety

1418274-28-8

C28H22Cl3N3O5

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