1-(4-FLUOROBENZYL)PIPERAZINE Property

Melting point:

64 °C

Boiling point:

112-114°C 2mm

Density 

1.103

refractive index 

1.5255-1.5275

Flash point:

122℃

pka

9.13±0.10(Predicted)

InChIKey

OOSZCNKVJAVHJI-UHFFFAOYSA-N

CAS DataBase Reference

70931-28-1(CAS DataBase Reference)

Safety

Hazard Codes 

Xn,Xi

Risk Statements 

22-36/37/38-20/21/22

Safety Statements 

26-36-36/37/39

RIDADR 

3263

WGK Germany 

2

HazardClass 

IRRITANT

HS Code 

29335990

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

1-(4-FLUOROBENZYL)PIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid after melting

Uses

Precursor involved in the synthesis of a variety of biologically active molecules including:• ;Chemokine antagonists1• ;Pyrido[1,2-a]benzimidazoles with cytotoxic and antiplasmodial activity2• ;Pyrimidine derivatives as cholinesterase and Aβ-aggregation inhibitors3• ;Chlorokojic acid derivatives with antibacterial and antiviral activities4• ;EGFR and Aurora A kinase inhibitors5• ;Neurokinin-2 receptor antagonists6

Uses

Precursor involved in the synthesis of a variety of biologically active molecules including:

• Chemokine antagonists
• Pyrido[1,2-a]benzimidazoles with cytotoxic and antiplasmodial activity
• Pyrimidine derivatives as cholinesterase and Aβ-aggregation inhibitors
• Chlorokojic acid derivatives with antibacterial and antiviral activities
• EGFR and Aurora A kinase inhibitors
• Neurokinin-2 receptor antagonists