2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE
- Product Name
- 2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE
- CAS No.
- 28948-61-0
- Chemical Name
- 2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE
- Synonyms
- 2-broMo-4-chlorothieno[3;2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE;Thieno[3,2-c]pyridine, 2-bromo-4-chloro-;2-bromo-4-chlorothieno[3,2-c]pyridine - [B5261]
- CBNumber
- CB2402448
- Molecular Formula
- C7H3BrClNS
- Formula Weight
- 248.53
- MOL File
- 28948-61-0.mol
2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE Property
- Melting point:
- 119 °C
- Boiling point:
- 355.2±37.0 °C(Predicted)
- Density
- 1.849±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- pka
- -1.38±0.40(Predicted)
- color
- Yellow
Safety
- Hazard Codes
- Xi
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B684873
- Product name
- 2-Bromo-4-chlorothieno[3,2-c]pyridine
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 070220
- Product name
- 2-Bromo-4-chlorothieno[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $227
- Updated
- 2021/12/16
- Product number
- W5157
- Product name
- 2-Bromo-4-chlorothieno[3,2-c]pyridine
- Packaging
- 1g
- Price
- $264
- Updated
- 2021/12/16
- Product number
- FB151003
- Product name
- 2-Bromo-4-chlorothieno[3,2-c]pyridine
- Packaging
- 500mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- 070220
- Product name
- 2-Bromo-4-chlorothieno[3,2-c]pyridine
- Purity
- 95%
- Packaging
- 500mg
- Price
- $357
- Updated
- 2021/12/16
2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE Chemical Properties,Usage,Production
Synthesis
28948-60-9
28948-61-0
General procedure for the synthesis of 2-bromo-4-chlorothieno[3,2-C]pyridine from 2-bromo-4-hydroxythieno[3,2-C]pyridine: Phosphorus oxychloride (4.08 g, 26.6 mmol) was slowly added dropwise to a mixture of 2-bromothieno[3,2-c]pyridin-4(5H)-one (2.04 g, 8.87 mmol), and the reaction was carried out at 0 °C. Subsequently, the reaction mixture was heated to 135 °C for 2.5 hours. After completion of the reaction, the mixture was carefully poured onto ice water. The precipitate was collected by filtration and dried to afford 1.78 g (80.7% yield) of the target product 2-bromo-4-chlorothieno[3,2-C]pyridine. The product was characterized by 1H NMR (270 MHz, CH3OH-d4): δ 7.67 (d, 1H), 7.88 (dddd, J = 6.33 Hz, 2H), 8.19 (d, J = 5.54 Hz, 1H); the mass spectrometry (MS) showed the molecular ion peak as 248.0 (M-H)+; and the high-performance liquid chromatography (HPLC) analysis showed the purity as 100%.
References
[1] Patent: WO2004/828, 2003, A1
2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE manufacturers
- Product
- 2-BROMO-4-CHLOROTHIENO[3,2-C]PYRIDINE 28948-61-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10