2,6-DIBROMO-3-HYDROXYPYRIDINE
- Product Name
- 2,6-DIBROMO-3-HYDROXYPYRIDINE
- CAS No.
- 6602-33-1
- Chemical Name
- 2,6-DIBROMO-3-HYDROXYPYRIDINE
- Synonyms
- 2,6-dibromopyridin-3-ol;3-Pyridinol, 2,6-dibromo-;2,6-DIBROMO-3-HYDROXYPYRIDINE;2,6-DIBROMO-3-HYDROXYPYRIDINE ISO 9001：2015 REACH
- CBNumber
- CB2443568
- Molecular Formula
- C5H3Br2NO
- Formula Weight
- 252.89
- MOL File
- 6602-33-1.mol
2,6-DIBROMO-3-HYDROXYPYRIDINE Property
- Melting point:
- 164.0 to 168.0 °C
- Boiling point:
- 369.3±37.0 °C(Predicted)
- Density
- 2.228±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 3.86±0.10(Predicted)
- color
- White to Light yellow
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D5174
- Product name
- 2,6-Dibromo-3-hydroxypyridine
- Purity
- >97.0%(T)
- Packaging
- 1g
- Price
- $84
- Updated
- 2025/07/31
- Product number
- D425775
- Product name
- 2,6-Dibromo-3-hydroxypyridine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- D425775
- Product name
- 2,6-Dibromo-3-hydroxypyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FD142833
- Product name
- 2,6-Dibromo-3-hydroxypyridine
- Packaging
- 500mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- D15667
- Product name
- 2,6-Dibromo-3-hydroxypyridine
- Packaging
- 5g
- Price
- $70
- Updated
- 2021/12/16
2,6-DIBROMO-3-HYDROXYPYRIDINE Chemical Properties,Usage,Production
Synthesis
109-00-2
6602-33-1
General procedure for the synthesis of 2,6-dibromo-3-hydroxypyridine from 3-hydroxypyridine: Ice-cold bromine (16.2 mL, 315 mmol) was added dropwise to a stirring 2.5 M sodium hydroxide solution (320 mL, 800 mmol). This mixed solution was then slowly added to a 2.5 M sodium hydroxide solution (110 mL, 275 mmol) containing 3-hydroxypyridine (10.0 g, 105 mmol). The reaction mixture was stirred at 0 °C for 1 hour, followed by continued stirring at room temperature for 4 hours. Upon completion of the reaction, a small amount of precipitate was removed by filtration. The filtrate was cooled and the pH was adjusted to 1 with concentrated hydrochloric acid, at which point a solid precipitated. The solid product was collected by filtration, washed with water, dried, and recrystallized from carbon tetrachloride to give 2,6-dibromo-3-hydroxypyridine (12.1 g, 46% yield) as a beige solid. The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ= 11.14 (br s, 1H), 7.47 (d, J = 8.0 Hz, 1H), 7.26 (d, J = 8.0 Hz, 1H); mass spectra (ES-ve) m/z: 250, 252, 254 (M-H)-.
References
[1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 15, p. 4298 - 4311
[2] Australian Journal of Chemistry, 1981, vol. 34, # 4, p. 927 - 932
[3] Patent: WO2010/56549, 2010, A1. Location in patent: Page/Page column 97
[4] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5630 - 5634
[5] Patent: WO2013/181931, 2013, A1. Location in patent: Page/Page column 40
2,6-DIBROMO-3-HYDROXYPYRIDINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2,6-DIBROMO-3-HYDROXYPYRIDINE manufacturers
- Product
- 2,6-DIBROMO-3-HYDROXYPYRIDINE 6602-33-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-09-26
- Product
- 2,6-DIBROMO-3-HYDROXYPYRIDINE 6602-33-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-07-11