ChemicalBook > CAS DataBase List > 3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER

3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER

Product Name
3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER
CAS No.
29269-17-8
Chemical Name
3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER
Synonyms
TRI(2-METHOXYCARBONYLETHYL)PHOSPHINE;Trimethyl3,3',3''-phosphinetriyltripropanoate;Trimethyl 3,3',3''-phosphineTriylTripropanoate;Propanoic acid, 3,3',3''-phosphinidynetris-, 1,1',1''-trimethyl ester;3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER;Propanoicacid,3,3',3''-phosphinidynetriChemicalbooks-,1,1',1''-trimethylester
CBNumber
CB2443593
Molecular Formula
C12H21O6P
Formula Weight
292.27
MOL File
29269-17-8.mol
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3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER Property

Boiling point:
365.4±37.0 °C(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
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Safety

HS Code 
2931499090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0085701
Product name
TRI(2-METHOXYCARBONYLETHYL)PHOSPHINE
Purity
95.00%
Packaging
1G
Price
$945.95
Updated
2021/12/16
Crysdot
Product number
CD50000193
Product name
Trimethyl3,3',3''-phosphinetriyltripropanoate
Purity
95%
Packaging
100mg
Price
$35
Updated
2021/12/16
BLDpharm
Product number
BD00780815
Product name
Trimethyl3,3',3''-phosphinetriyltripropanoate
Purity
95%
Packaging
100mg
Price
$51
Updated
2021/12/16
Crysdot
Product number
CD50000193
Product name
Trimethyl3,3',3''-phosphinetriyltripropanoate
Purity
95%
Packaging
250mg
Price
$68
Updated
2021/12/16
Crysdot
Product number
CD50000193
Product name
Trimethyl3,3',3''-phosphinetriyltripropanoate
Purity
95%
Packaging
1g
Price
$206
Updated
2021/12/16
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3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

67-56-1

51805-45-9

29269-17-8

General procedure for the synthesis of trimethyl 3,3',3''-phosphono-tripropionate from methanol and tris(2-carboxyethyl)phosphine hydrochloride: tris(2-carboxyethyl)phosphine hydrochloride (TCEP) (7.0 g, 24.42 mmol) was co-evaporated with ethanol (EtOH) (2 × 100 mL) and subsequently dissolved in methanol (CH3OH) (200 mL) at 4 °C . Thionyl chloride (SOCl2) (9.0 mL, 122.29 mmol) was slowly added to this solution. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was concentrated and dried under vacuum to afford trimethyl 3,3',3''-phosphonyl tripropionate (7.0 g, 98% yield). The product was confirmed by electrospray ionization mass spectrometry (ESI MS) with an observed m/z of 293.2 (M+H)+.

References

[1] Patent: WO2015/28850, 2015, A1. Location in patent: Page/Page column 81

3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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29269-17-8, 3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTERRelated Search:


  • 3-[BIS-(2-METHOXYCARBONYL-ETHYL)-PHOSPHANYL]-PROPIONIC ACID METHYL ESTER
  • Propanoic acid, 3,3',3''-phosphinidynetris-, 1,1',1''-trimethyl ester
  • Trimethyl 3,3',3''-phosphineTriylTripropanoate
  • TRI(2-METHOXYCARBONYLETHYL)PHOSPHINE
  • Propanoicacid,3,3',3''-phosphinidynetriChemicalbooks-,1,1',1''-trimethylester
  • Trimethyl3,3',3''-phosphinetriyltripropanoate
  • 29269-17-8
  • C12H21O6P
  • C12H22O6PCl