ChemicalBook > CAS DataBase List > 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE

1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE

Product Name
1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE
CAS No.
346451-15-8
Chemical Name
1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE
Synonyms
Cetirizine -EP-Imp-D;USP Cetirizine Dimer;Cetirizine IMpurity D;Cetirizine Impurity97;Cetirizine Impurity 12;Meclozine EP Impurity F;Buclizine EP Impurity A HCl;Buclizine HCl IMpurity-A(BP/EP);1,4-Bis[(4-chlorophenyl)phenylmethy;Meclozine Dihydrochloride Impurity F
CBNumber
CB2444550
Molecular Formula
C30H28Cl2N2
Formula Weight
487.46
MOL File
346451-15-8.mol
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1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE Property

Melting point:
>180°C (dec.)
Boiling point:
270-275 °C(Press: 1 Torr)
Density 
1.228±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, Refrigerator, Under inert atmosphere
solubility 
Chloroform (Slightly, Heated, Sonicated), DMSO (Slightly, Heated), Methanol (Slightly)
form 
Solid
pka
5.85±0.10(Predicted)
color 
White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Alfa Aesar
Product number
H63961
Product name
1,4-Bis[alpha-(4-chlorophenyl)benzyl]piperazine dihydrochloride, 97%
Packaging
1g
Price
$79.65
Updated
2024/03/01
Alfa Aesar
Product number
H63961
Product name
1,4-Bis[alpha-(4-chlorophenyl)benzyl]piperazine dihydrochloride, 97%
Packaging
5g
Price
$312.65
Updated
2024/03/01
Alfa Aesar
Product number
H63961
Product name
1,4-Bis[alpha-(4-chlorophenyl)benzyl]piperazine dihydrochloride, 97%
Packaging
250mg
Price
$28.65
Updated
2024/03/01
Biosynth Carbosynth
Product number
FB53638
Product name
1,4-Bis[(4-Chlorophenyl)Phenylmethyl]Piperazine Dihydrochloride
Packaging
100mg
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB53638
Product name
1,4-Bis[(4-Chlorophenyl)Phenylmethyl]Piperazine Dihydrochloride
Packaging
2g
Price
$320
Updated
2021/12/16
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1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine is an impurity of Buclizine (B689450), an antiemetic agent.

1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDE Suppliers

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346451-15-8, 1,4-BIS[(4-CHLOROPHENYL)PHENYLMETHYL]PIPERAZINE DIHYDROCHLORIDERelated Search:

iperazineacetic acid, 4-[(4- chlorophenyl)phenylMethyl]- 1-Piperazineethanol,4-[(2-chlorophenyl)(3-chlorophenyl)methyl]-, hydrochloride (1:2) 4-CHLORODIPHENYLAMINE Cetirizine Methyl Ester SNPT-1809279-00-2 SNPT-1809278-35-0 (R)-De(carboxyMethyl) Cetirizine Ethanol Dihydrochloride 4-Chlorobenzophenone rac Cetirizine N-Oxide > 70% by HPLC (Mixture of Diastereomers) Cetirizine Glycerol Ester Cetirizine Ethyl Ester (USP RC A) (RS)-2-[2-[4-[(2-Chloro-phenyl)phenylMethyl]piperazin-1-yl]ethoxy]aceticAcidDihydrochloride (S)-Cetirizine Dihydrochloride N-(2,4-Dichlorophenyl)benzenamine Levocetetrizine N-Oxide Cetirizine EP Impurity E 2(2-HYDROXYETHOXY)ACETAMIDE Cetirizine EP Impurity B(base)

  • Buclizine HCl IMpurity-A(BP/EP)
  • 1,4-Bis[^a-(4-chlorophenyl)benzyl]piperazine dihydrochloride, 97%
  • Cetirizine IMpurity D
  • Piperazine, 1,4-bis[(4- chlorophenyl)phenylMethyl]-
  • 1,4-Bis[alpha-(4-chlorophenyl)benzyl]piperazine dihydrochloride
  • Cetirizine Dihydrochloride impurity D
  • 1,4-Bis[(4-chlorophenyl)phenylmethyl]piperazine DiHCl
  • Cetirizine Impurity 12
  • Buclizine EP Impurity A HCl
  • Cetirizine Impurity 12（Cetirizine EP Impurity D）
  • Cetirizine -EP-Imp-D
  • 1,4-Bis[(4-chlorophenyl)phenylmethy
  • 1,4-Bis[^a-(4-chlorophenyl)benzyl]piperazinedihydrochloride,97%
  • USP Cetirizine Dimer
  • Cetirizine EP Impurity D (free base ) /Levocetirizine - Impurity D (Freebase)
  • Cetirizine Impurity97
  • Meclozine EP Impurity F
  • 1,4-Bis(4-chlorobenzhydryl)piperazineQ: What is 1,4-Bis(4-chlorobenzhydryl)piperazine Q: What is the CAS Number of 1,4-Bis(4-chlorobenzhydryl)piperazine
  • Meclozine Dihydrochloride Impurity F
  • Meclozine Dihydrochloride EP Impurity F
  • Cetirizine EP Impurity-D (free base)
  • Cetirizine Dihydrochloride EP Impurity D
  • Cetirizine EP Impurity D Cetirizine Dimer Impurity (USP)
  • 346451-15-8
  • C30H28Cl2N2
  • C30H30Cl4N2
  • C30H28Cl2N22HCl
  • C30H28Cl2N22ClH
  • Aromatics, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals